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TTD Drug ID: DAP000087

Drug Information
NameYohimbine    
SynonymsAphrosol; NCGC00025018-05; Johimbin; Yohimban-16-alpha-carboxylic acid, 17-alpha-hydroxy-, methyl ester; SPBio_002647; Yocon; methyl (16alpha,17alpha)-17-hydroxyyohimban-16-carboxylate; (16alpha,17alpha)-17-Hydroxy-yohimban-16-carboxylic acid methyl ester; CID8969; Baron-X; Prestwick0_000584; KBio3_001032; Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16alpha,17alpha)- (9CI); C09256; Bio1_000455; APHRODINE; KBio2_000576; BPBio1_000472; KBio3_001031; KBio2_005712; NCGC00025018-06; AC1L1S1D; 4-25-00-01237 (Beilstein Handbook Reference); Yohimban-16alpha-carboxylic acid, 17alpha-hydroxy-, methyl ester (8CI); CHEBI:10093; Yohimbine; SMR000058527; Benz[g]indolo[2,3-a]quinolizine, yohimban-16-carboxylic acid deriv.; HMS1990N17; IDI1_002213; Dayto himbin; HMS2089G19; (16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester; 146-48-5; DB01392; Yohimbine (DCF); CHEMBL15245; Prestwick1_000584; nchembio705-2; I14-13374; SMR000470778; Bio1_000944; 65-19-0; BRD-K35586044-001-02-6; InChI=1/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12?,15?,17?,18-,19+/m0/s; (+)-Yohimbin; Actibine; BRN 0097276; MLS001333983; (+)-Yohimbine; EINECS 205-672-0; 17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester; STOCK1N-51304; LS-162738; Yoman; Bio2_000458; HMS1792N17; 2-Hydroxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydro-indolo[2',3':3,4]pyrido[1,2-b]isoquinoline-1-carboxylic acid methyl ester; NSC19509; MolPort-001-794-653; Yohimbic acid methyl ester; Thybine; KBioSS_000576; BRD-K35586044-003-03-0; nchembio.188-comp13; Yovital; KBio2_003144; Yohimban-16-.alpha.-carboxylic acid, 17-.alpha.-hydroxy-, methyl ester; BCBcMAP01_000032; Bio1_001433; Yohimar; Quebrachine; Aphrodyne; Prestwick3_000584; HMS1362N17; SMP1_000320; methyl 17alpha-hydroxyyohimban-16alpha-carboxylate; Prestwick2_000584; KBioGR_000576; 17-Hydroxyyohimban-16-carboxylic acid methyl ester; Corynine; Yohimbol-16alpha-carboxylic acid, methyl ester (6CI); UNII-2Y49VWD90Q; BSPBio_000428; 17-Hydroxy-yohimbane-16-carboxylic acid methyl ester; Lopac0_001210; Bio2_000938; NCGC00025018-07; Yohimex; trans-Quinolizidine yohimbine; Yohimban-16-carboxylic acid, 17-hydroxy-, methyl ester, (16alpha,17alpha)-; D08685; Quebrachin; MLS000728591; BSPBio_001236; Yohimbin    
CompanyPalisades Pharmaceuticals Inc    
IndicationMale impotenceApproved    [1]
Structure

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Therapeutic ClassMydriatics    
CAS NumberCAS 146-48-5
FormularC21H26N2O3    
PubChem Compound IDCID 8969.    
PubChem Substance IDSID 11447.    
ChEBI10093;    
SuperDrug ATC IDG04BE04;    
SuperDrug CAS ID000146485;    
TargetAlpha-2 adrenergic receptorAntagonist[2][3][1]
Ref 1Interest of alpha2-adrenergic agonists and antagonists in clinical practice: background, facts and perspectives. Curr Top Med Chem. 2007;7(2):187-94. To Reference
Ref 2Acute neurotoxicity after yohimbine ingestion by a body builder. Clin Toxicol (Phila). 2009 Jul 30. [Epub ahead of print] To Reference
Ref 3Alpha2-adrenergic receptors attenuate secretagogue-induced endocytosis and promote exocytosis of intestinal NHE2 and NHE3. J Pharmacol Exp Ther. 2009 Jun 25. [Epub ahead of print] To Reference



 

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