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TTD Drug ID: DAP000097

Drug Information
NameNaloxone    
SynonymsUNII-36B82AMQ7N; Naloxonum [INN-Latin]; N-Allyl-4,5alpha-epoxy-3,14-dihydroxy-6-morphinanon; (5alpha)-3,14-dihydroxy-17-prop-2-en-1-yl-4,5-epoxymorphinan-6-one; Naloxona; CID5284596; Narcanti; l-N-Allyl-7,8-dihydro-14-hydroxynormorphinone; Prestwick2_000111; EN 1530 base; 17-allyl-3,14-dihydroxy-4,5alpha-epoxymorphinan-6-one; Naloxone [INN:BAN]; Morphinan-6-one, 4,5-alpha-epoxy-3,14-dihydroxy-17-(2-propenyl)-; CHEBI:7459; l-N-Allyl-14-hydroxynordihydromorphinone; 357-08-4 (hydrochloride); Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, (5.alpha.)-; Narcon; (-)-Naloxone; 1-N-Allyl-14-hydroxynordihydromorphinone; Naloxonum; CHEMBL80; DB01183; BRD-K67511046-003-03-7; Naloxone (INN); NCGC00024674-02; Morphinan-6-one, 4,5.alpha.-epoxy-3,14-dihydroxy-17-(2-propenyl)-; Narcan; SMP1_000205; Nalone; NSC 70413; Morphinan-6-one, 17-allyl-4,5.alpha.-epoxy-3,14-dihydroxy-; EINECS 207-365-7; HSDB 3279; NSC70413; SPBio_002061; 3,14-dihydroxy-17-(prop-2-en-1-yl)-4,5alpha-epoxymorphinan-6-one; Morphinan-6-one, 17-allyl-4,5alpha-epoxy-3,14-dihydroxy-; Normorphinone, N-allyl-7,8-dihydro-14-hydroxy-, (-)-; 1-N-Allyl-7,8-dihydro-14-hydroxynormorphinone; Prestwick3_000111; Naloxone HCl; HMS2090F20; 17-Allyl-4,5alpha-epoxy-3,14-dihydroxymorphinan-6-one; LS-187184; 465-65-6; BRN 1089071; BIDD:GT0110; Prestwick1_000111; C07252; l-Naloxone; Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, (5alpha)-; BPBio1_000136; Normorphinone, N-allyl-dihydro-14-hydroxy-; N-Allyl-noroxymorphone; 12-Allyl-7,7a,8,9-tetrahydro-3,7a-dihydroxy-4aH-8,9c-iminoethanophenanthro(4,5-bcd)furanone; naloxone; STOCK1N-69923; n-Allylnoroxymorphone; D08249; Morphinan-6-one, 4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)-, (5alpha)- (9CI); Morphinan-6-one, 4,5alpha-epoxy-3,14-dihydroxy-17-(2-propenyl)-; 12-Allyl-7,7a,8,9-tetrahydro-3,7a-dihydroxy-4aH-8,9c-iminoethanophenanthro[4,5-bcd]furan-5(6H)-one; Morphinan-6-one, 17-allyl-4,5alpha-epoxy-3,14-dihydroxy- (8CI); LS-92141; Prestwick0_000111; DBL Naloxone; 17-Allyl-4,5-alpha-epoxy-3,14-dihydroxymorphinan-6-one; 4aH-8,9c-Iminoethanophenanthro[4,5-bcd]furan-5(6H)-one, N-allyl-7,7a,8,9-tetrahydro-3,7a-dihydroxy-; Naloxona [INN-Spanish]; BSPBio_000122; MolPort-002-536-640; DBL Naloxone (TN); (5alpha)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one; Nalossone; Nalossone [DCIT]; (-)-N-allyl-14-hydroxynordihydroxymorphinan-6-one; PDSP2_001520    
Trade NameNarcan; Nalone; Narcanti    
CompanyBristol Meyers Squibb    
IndicationNarcotic depressionApproved    [1]
Structure

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Therapeutic ClassAntinarcotic Agents    
CAS NumberCAS 465-65-6
FormularC19H21NO4    
PubChem Compound IDCID 5284596.    
PubChem Substance IDSID 9461.    
ChEBI7459;    
SuperDrug ATC IDV03AB15;    
SuperDrug CAS ID000465656;    
TargetMu-type opioid receptorAntagonist[2][3]
Ref 1Opioid drug utilization and cost outcomes associated with the use of buprenorphine-naloxone in patients with a history of prescription opioid use. J Manag Care Pharm. 2008 Mar;14(2):186-94. To Reference
Ref 2OxyContin abuse and overdose. Postgrad Med. 2009 Mar;121(2):163-7. To Reference
Ref 3Mu opioid receptor antagonists: recent developments. ChemMedChem. 2007 Nov;2(11):1552-70. To Reference



 

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