Therapeutic Targets Database
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TTD Drug ID: DAP000102

Drug Information
NameTerfenadine    
SynonymsLopac0_001213; Rapidal; SMR000058260; Stadapharm Brand of Terfenadine; Terfedura; SPBio_002155; Seldane (TN); AC1L1KA8; Triludan; Merck dura Brand of Terfenadine; Wolff Brand of Terfenadine; UNII-7BA5G9Y06Q; T9652_SIGMA; RMI 9918; ratiopharm Brand of Terfenadine; Prestwick0_000138; NCGC00089746-02; DB00342; Teldane; Terfenadin Heumann; Terfemundin; alpha-(p-tert-Butylphenyl)-4-(hydroxydiphenylmethyl)-1-piperidinebutanol; MLS000028499; Bial Brand of Terfenadine; 50679-08-8; 1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-ol; Prestwick_460; Cantabria Brand of Terfenadine; NCGC00016064-04; Aliud Brand of Terfenadine; MDL-9918; Oprea1_343139; NCGC00089746-03; Terfenadin Stada; D016593; Cyater; 1-(4-tert-butylphenyl)-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butan-1-ol; ct Arzneimittel Brand of Terfenadine; C32H41NO2; Hoechst Brand of Terfenadine; Terfenadin AL; alpha-(4-[1,1-Dimethylethyl]phenyl)-4-[hydroxydiphenylmethyl]-1-piperidinebutanol; MLS001148415; NCGC00016064-08; CID5405; .alpha.-(4-(1,1-dimethylethyl)phenyl)-4-(hydroxydiphenyl-methyl)-1-piperidine butanol; terfenadin von ct; Terfenidine; alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperidinebutanol; Balkis Saft Spezial; Terfenadin-ratiopharm; Terfenadina; 1-(p-tert-Butylphenyl)-4-(4'-(alpha-hydroxydiphenylmethyl)-1'-piperidyl)butanol; Terfenadina [INN-Spanish]; Hisfedin; Terfenadinum; NSC665802; HMS1568K18; Prestwick2_000138; EU-0101213; CHEMBL17157; BIM-0051180.0001; Terfex; LS-114369; ct-Arzneimittel Brand of Terfenadine; KBio1_001011; NCGC00089746-04; Mundipharma Brand of Terfenadine; Ternadin; T 9652; AB00052367; HSDB 6508; terfenadine; ST50307835; 1-Piperidinebutanol, .alpha.-[4-(1,1-dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-; Aldaban; Prestwick1_000138; Terfenadinum [INN-Latin]; Terfenadine [USAN:BAN:INN:JAN]; Teldanex; HMS2089I14; Sigma-Tau Brand of Terfenadine; NCI60_022784; EINECS 256-710-8; Seldane; RMI-9918; alpha-[4-(1,1-Dimethylethyl)phenyl]-4-(hydroxydiphenylmethyl)-1-piperidinebutanol; CHEBI:119569; MolPort-002-904-065; L000888; Prestwick3_000138; DivK1c_001011; 1-(4-tert-Butylphenyl)-4-(4-(alpha-hydroxybenzhydryl)piperidino)-butan-1-ol; Heumann Brand of Terfenadine; BSPBio_000216; 1-[4-(1,1-dimethylethyl)phenyl]-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}butan-1-ol; Sigma Tau Brand of Terfenadine; D00521; alpha-(4-(1,1-Dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-1-piperdinebutanol; HMS2093I11; Terfenadine (JAN/USAN/INN); AC1Q1LZA; Allerplus; IDI1_001011; BRN 5857899; AC-15791; Dolorgiet Brand of Terfenadine; C07463; MDL 9918; NINDS_001011; BRD-A06352418-001-03-6; 1-Piperidinebutanol, alpha-(4-(1,1-dimethylethyl)phenyl)-4-(hydroxydiphenylmethyl)-; HMS503K03; Terfen; BPBio1_000238; RMI9918; Terdin    
Trade NameSeldane; Triludan; Teldane    
CompanyMarion Merrell. Dow, Inc.    
IndicationAllergiesApproved    [1]
Structure

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Therapeutic ClassAntihistamines    
CAS NumberCAS 50679-08-8
FormularC32H41NO2    
PubChem Compound IDCID 5405.    
PubChem Substance IDSID 9666.    
SuperDrug ATC IDR06AX12;    
SuperDrug CAS ID050679088;    
TargetHistamine H1 receptorAntagonist[2][3]
Ref 1Comparative tolerability of second generation antihistamines. Drug Saf. 1999 May;20(5):385-401. To Reference
Ref 2Small mouse cholangiocytes proliferate in response to H1 histamine receptor stimulation by activation of the IP3/CaMK I/CREB pathway. Am J Physiol Cell Physiol. 2008 Aug;295(2):C499-513. Epub 2008 May 28. To Reference
Ref 3Second-generation antihistamines: a comparative review. Drugs. 1999 Jan;57(1):31-47. To Reference



 

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