Therapeutic Targets Database
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TTD Drug ID: DAP000108

Drug Information
NameTamoxifen    
SynonymsHMS1792J11; C07108; Nourytam; Tamone; ,citrate; (Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine (IUPAC); Tamoxifeno [INN-Spanish]; BPBio1_000278; trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine; Novo-Tamoxifen; NCGC00024928-03; Diemon; Ethylamine, N,N-dimethyl-2-(p-(1,2-diphenyl-1-butenyl)phenoxy)-, (Z)-; BSPBio_001150; 1ya4; Tamoxifen [INN:BAN]; Tamoxifen and its salts; UNII-094ZI81Y45; BRD-K93754473-001-02-9; CHEBI:41774; D08559; Prestwick3_000146; nchembio.76-comp1; 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene; cMAP_000044; L024126; Retaxim; (Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene; Oncomox; HSDB 6782; Lopac0_001203; Spectrum5_001417; BIDD:PXR0003; BRD-K93754473-048-05-3; 1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene; ST50511785; Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)-; 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine; LS-393; Spectrum5_002043; NCGC00024928-07; NSC727681; Gen-Tamoxifen; Crisafeno; Citofen; Tamoxifen (INN); MolPort-003-850-384; Prestwick2_000146; (Z)-2-(4-(1,2-diphenylbut-1-enyl)phenoxy)-N,N-dimethylethanamine; NCGC00024928-01; BSPBio_001982; CCRIS 3275; IDI1_002170; Tomaxithen; Tamoxifen (TN); TAMOXIFEN (TAMOXIFEN CITRATE (54965-24-1)); SMR000059172; QTL1_000079; Pms-Tamoxifen; Tamoxifenum; BSPBio_000252; DB00675; nchembio732-comp3; C26H29NO; HMS1362J11; MLS001332536; Tamoxifenum [INN-Latin]; NCGC00024928-05; Tamoxifene [INN-French]; ICI 47699; NCGC00024928-09; tamoxifen; trans-Tamoxifen; CID2733526; EINECS 234-118-0; Tamoxifene; AC1MBZ3R; Tamoxifeno; HMS1990J11; Tamoxifen (Z); ICI-47699; TRANS FORM OF TAMOXIFEN; Tocris-0999; 54965-24-1 (citrate); Tamizam; BIDD:GT0009; Novaldex; Valodex; Istubol; MLS001332535; CHEMBL83; NCGC00024928-08; Tamoxen; T5648_SIGMA; 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine; (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine; IDI1_000258; (Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine; 1-p-.beta.-Dimethylamino-ethoxyphenyl-trans-1,2-diphenylbut-1-ene; BIDD:ER0008; 10540-29-1; NCGC00024928-12; nchembio.140-comp7; Tamoplex (TN); (Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE; Ethanamine, 2-(4-((1Z)-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-; NCGC00024928-04; HMS2090N08; UPCMLD-DP027; Nolvadex-D; ICI-46,474    
Trade NameNolvadex; Istubal; Valodex    
CompanyAstraZeneca plc    
IndicationBreast cancerApproved    [1]
Structure

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Therapeutic ClassAntineoplastic Agents    
CAS NumberCAS 10540-29-1
FormularC26H29NO    
PubChem Compound IDCID 2733526.    
PubChem Substance IDSID 9319.    
ChEBI41774;    
SuperDrug ATC IDL02BA01;    
SuperDrug CAS ID010540291;    
TargetEstrogen receptorAntagonist[2][3]
Ref 1Rational management of endocrine resistance in breast cancer: a comprehensive review of estrogen receptor biology, treatment options, and future directions. Cancer. 2008 Nov 1;113(9):2385-97. To Reference
Ref 2Modulators of vascular sex hormone receptors and their effects in estrogen-deficiency states associated with menopause. Recent Pat Cardiovasc Drug Discov. 2008 Nov;3(3):165-86. To Reference
Ref 3Chemoprevention for high-risk women: tamoxifen and beyond. Breast J. 2001 Sep-Oct;7(5):311-20. To Reference



 

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