Therapeutic Targets Database
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TTD Drug ID: DAP000116

Drug Information
NameGentamicin    
SynonymsGentamar; AR-1F8593; Gentavet; 1403-66-3; D08013; Gentamycinum; HSDB 3087; Gentamicina; O-2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-alpha-D-ribo-heptopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-2-deoxy-D-streptamine; UNII-T6Z9V48IKG; 2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol; 4,6-diamino-3-{[3-deoxy-4-c-methyl-3-(methylamino)pentopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside; Gentak; LS-71146; MolPort-005-934-296; Genoptic Liquifilm; Gentamicine [INN-French]; G-Myticin; Gentamicin (TN); CHEBI:27412; CID441305; (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl (6x)-2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-alpha-D-erythro-heptopyranoside; gentamicin; Refobacin; Gentamicinum; DB00798; Gentamicins; Uromycine; Ocu-Mycin; EINECS 215-765-8; Apogen; GENTAMYCIN; AC1Q57VC; U-Gencin; C21H43N5O7; Gentamicinum [INN-Latin]; Gentacidin; Bristagen; Gentamycin-creme [German]; Gentamycin-creme; (1R,2S,3S,4R,6S)-4,6-diamino-3-[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyloxy]-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)-beta-L-lyxo-heptopyranoside; Cidomycin; Gentamicin (BAN); Gentamicin C1; Refobacin TM; Gentamicine; AC-13386; AC1L1G02; Spectro-Genta; Garamycin Otic Solution; Garamycin; Garasol; 25876-10-2; Gentocin; CHEMBL195892; Gentamcin Sulfate; (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol; G-Mycin; Gentamicina [INN-Spanish]; nchembio.274-comp5; Gentacycol; Gentafair; AC1L9AXS; CID3467; Alcomicin; Jenamicin; Genoptic S.O.P.; Gentamicin sulphate sterile    
Trade NameGaramycin    
CompanySandoz    
IndicationBacterial InfectionApproved    [1]
Structure

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Therapeutic ClassAnti-Bacterial Agents    
CAS NumberCAS 1403-66-3
FormularC21H43N5O7    
PubChem Compound IDCID 441305.    
PubChem Substance IDSID 8144516.    
ChEBI17833;    
SuperDrug ATC IDD06AX07;    
SuperDrug CAS ID001403663;    
Target73-kDa molecular chaperone HSP73Inhibitor[2]
Ref 1How many modes of action should an antibiotic have? Curr Opin Pharmacol. 2008 Oct;8(5):564-73. Epub 2008 Jul 30. To Reference
Ref 273-kDa molecular chaperone HSP73 is a direct target of antibiotic gentamicin. J Biol Chem. 2004 Apr 23;279(17):17295-300. Epub 2004 Feb 13. To Reference



 

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