Therapeutic Targets Database
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TTD Drug ID: DAP000139

Drug Information
NameAmlodipine    
SynonymsAmlodipine Free Base; KBio3_001947; AC1Q32ZS; HMS2052N03; LS-131183; 3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate; Lipinox; Amlor; KBioGR_001643; NCGC00165957-01; CHEMBL1491; Amlodis; amlodipine; NCGC00165957-02; 3-Ethyl-5-methyl ( -)-2-((2-aminoethoxy)methyl)-4-(2-chlorphenyl)-1,4-dihydro-6-methyl-3,5-pyridindicarboxylat; Spectrum2_000486; D07450; AMLODIPINE BASE; 3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester; Amlodipino [Spanish]; AC1L1D26; Amlodipino; -3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine; Amlodipinum; Intervask; I14-0798; SPBio_000351; Racemic Amlodipine; BIDD:GT0810; UNII-1J444QC288; BRD-A22032524-074-03-2; Spectrum4_001132; Amlocard; MolPort-001-792-963; Amlodipine [INN:BAN]; NCGC00165957-03; Amlodipine (INN); CPD000469198; 3-Ethyl-5-methyl ( -)-2-((2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate; SAM001246705; AC-4535; 88150-42-9; Ambap88150-42-9; BSPBio_002727; 3-ethyl 5-methyl 2-{[(2-aminoethyl)oxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate; R,S)-Amlodipine; ()-Amlodipine; 2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl); HMS2089H07; SMR000469198; MLS001401409; 3-Ethyl-5-methyl (.+/-.)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate; 3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester; Spectrum3_001004; C06825; Norvasc (TN); Coroval; DB00381; 3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate; 88150-47-4 (maleate (1:1)); Amlopres; 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate; UK-4834011; CID2162; CHEBI:2668; BRD-A22032524-074-02-4; Spectrum5_001550; Amlodipinum [Latin]    
Trade NameDailyvasc; Norvasc; Istin; Perivasc    
CompanyDainippon Sumitomo    
IndicationHypertension and anginaApproved    [1]
Structure

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Click to save drug structure in 2D MOL format
   
Therapeutic ClassAntihypertensive Agents    
CAS NumberCAS 88150-42-9
FormularC20H25ClN2O5    
PubChem Compound IDCID 2162.    
PubChem Substance IDSID 9043.    
SuperDrug ATC IDC08CA01;    
SuperDrug CAS ID088150429;    
TargetCalcium channelBlocker[2][3]
Ref 1Antihypertensive efficacy of olmesartan medoxomil or valsartan in combination with amlodipine: a review of factorial-design studies. Curr Med Res Opin. 2009 Jan;25(1):177-85. To Reference
Ref 2A first drug combination for the treatment of arterial hypertension with a calcium channel antagonist (amlodipine besylate) and an angiotensin receptor blocker (valsartan): Exforge. Rev Med Liege. 2007 Nov;62(11):688-94. To Reference
Ref 3Benidipine, an anti-hypertensive drug, inhibits reactive oxygen species production in polymorphonuclear leukocytes and oxidative stress in salt-loaded stroke-prone spontaneously hypertensive rats. Eur J Pharmacol. 2008 Feb 2;580(1-2):201-13. Epub 2007 Nov 1. To Reference



 

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