Therapeutic Targets Database
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TTD Drug ID: DAP000142

Drug Information
NameFlunarizine    
Synonyms1-[bis(4-fluorophenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine; BPBio1_000336; DB04841; 30484-77-6 (di-hydrochloride); CID941361; Flunarizin; Novo-Flunarizine; HMS1989D03; Flunarizine (INN); CHEMBL30008; BRD-K12184470-300-01-8; 40218-96-0; Sibelium; HMS2089H21; HMS1791D03; Vertix; AC1LIZWP; NCGC00024308-06; D07971; NCGC00018102-09; NCGC00024308-04; Issium; NCGC00024308-07; AR-1B9446; EINECS 254-842-0; Spectrum5_001570; Apo-flunarizine capsules; Flunarizine [INN:BAN]; BRD-K29582677-001-02-7; Zinasen; 1-(Bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine; EINECS 257-937-5; Flunarizinum; Piperazine, 1-(bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propenyl)-; HMS1361D03; LS-110464; BCBcMAP01_000120; BSPBio_000304; Lopac0_000527; NCGC00024308-05; Flunarizina [INN-Spanish]; CHEBI:138764; IDI1_000043; flunarizine; BRD-K29582677-300-05-6; Fluvert; Bio-0741; Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-(3-phenyl-2-propenyl)-, (E)-; MolPort-000-732-712; 52468-60-7; 5343-57-7; Piperazine, 1-[bis(4-fluorophenyl)methyl]-4-[(2E)-3-phenyl-2-propenyl]-; AC1Q4NMD; Sibelium (TN); AC-1283; (E)-1-(Bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propenyl)piperazine; C26H26F2N2; KST-1B4966; Flunarizinum [INN-Latin]; R-14950; 1-[bis(4-fluorophenyl)methyl]-4-(3-phenylprop-2-en-1-yl)piperazine; Prestwick2_000312; BSPBio_003096; (E)-1-[Bis-(p-fluorophenyl)methyl]-4-cinnamylpiperazine; Flunarizina; Piperazine, 1-(bis(4-fluorophenyl)methyl)-4-(3-phenyl-2-propenyl)-, (E)-; IDI1_033811; Flufenal; BSPBio_001341; Prestwick3_000312    
Trade NameSibelium    
CompanyJanssen Pharmaceutica    
IndicationMigraineApproved    [1]
Structure

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Therapeutic ClassAnticonvulsants    
CAS NumberCAS 52468-60-7
FormularC26H26F2N2    
PubChem Compound IDCID 941361.    
PubChem Substance IDSID 181267.    
SuperDrug ATC IDN07CA03;    
SuperDrug CAS ID052468607;    
TargetVoltage-dependent T-type calcium channelBlocker[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 012102 To Reference
Ref 2Positive Allosteric Interaction of Structurally Diverse T-Type Calcium Channel Antagonists. Cell Biochem Biophys. 2009 Jul 7. [Epub ahead of print] To Reference
Ref 3Migraine prophylaxis with calcium antagonists: a haemodynamic study using transcranial Doppler ultrasound. Rev Neurol. 2004 Feb 16-29;38(4):316-9. To Reference



 

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