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TTD Drug ID: DAP000144

Drug Information
NameStreptomycin    
SynonymsHMS2090P05; CHEBI:405369; 2-[(1S,2S,3R,4S,5S,6R)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine; Streptomyzin [German]; Streptomycin Sesquisulfate Hydrate; NCGC00179603-02; MolPort-002-525-998; O-2-Deoxy-2-(methylamino)-.alpha.-L-glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-.alpha.-L-lyxofuranosyl-(1->4)-N,N'-bis(aminoiminomethyl)-D-streptamine and Liposome; AC1O7EO6; Streptomycin, Sulfate Salt; CID6426892; EPA Pesticide Chemical Code 006306; 3810-74-0; Streptomycin & Propolis; ACon1_001297; Strepcen; AC1Q29OE; NSC 14083; CHEMBL1201194; N,N'''-[(1R,2R,3S,4R,5R,6S)-4-{5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyloxy}-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine; SPBio_002242; NSC14083; STREPTOMYCIN SULFATE (2:3) SALT; D-Streptamine, O-2-deoxy-2-(methylamino)-.alpha.-L-glucopyranosyl-(1->2)-O-5-deoxy-3-C-formyl-.alpha.-L-lyxofuranosyl-(1->4)-N,N'-bis(aminoiminomethyl)-; 57-92-1; NCGC00179603-01; CID6602485; Streptomicina; Agrimycin; NCGC00159339-02; UNII-Y45QSO73OB; 4-18-00-07540 (Beilstein Handbook Reference); Prestwick2_000321; HSDB 1768; Streptomycin (INN); 82958-69-8; AC1O52TO; Estreptomicina [INN-Spanish]; CHEBI:17076; N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl]-3-C-formyl-alpha-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidine; Streptomycin A sulfate; 3810-74-0 (sulfate (2:3) salt); Bio-0644; Streptomycin A; D-Streptamine, O-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1-2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1-4)-N,N'-bis(aminoiminomethyl)-; AC1L2EK8; Streptomycin sulfate; Hokko-mycin; 2,4-Diguanidino-3,5,6-trihydroxycyclohexyl 5-deoxy-2-O-(2-deoxy-2-methylamino-alpha-L-glucopyranosyl)-3-C-formyl-beta-L-lyxopentanofuranoside; CID19649; Streptomicina [Italian]; AC1L1LKU; Agrept; D-Streptamine, O-2-deoxy-2-(methylamino)-alpha-L-glucopyranosyl-(1.fwdarw.2)-O-5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl-(1.fwdarw.4)-N,N'-bis(aminoiminomethyl)-; Gerox; Prestwick3_000321; DB01082; Prestwick1_000321; Streptomycin sulphate; streptomycin; D08531; BSPBio_000321; CHEMBL173; C00413; CCRIS 5730; Streptomycin (TN); Streptomycinum; BRN 0074498; LS-187084; Streptomycin [INN:BAN]; Streptomycine; C21H39N7O12; [2-deoxy-2-(dimethylamino)-alpha-L-glucopyranosyl]-(1->2)-[5-deoxy-3-C-formyl-alpha-L-lyxofuranosyl]-(1->4)-{N',N'''-[(1,3,5/2,4,6)-2,4,5,6-tetrahydroxycyclohexane-1,3-diyl]diguanidine}; 12672-24-1; Streptomyzin; 2-[(1S,4S)-5-(diaminomethylideneamino)-2-[(2R,5S)-3-[(2S,5R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-3,4,6-trihydroxycyclohexyl]guanidine; 47816-81-9; LS-147053; Prestwick0_000321; Neodiestreptopab; CID5999; Caswell No. 804; BPBio1_000355; 2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine; EINECS 200-355-3; 2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2S,3S,4S,5R)-3-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine; Streptomycin & EEP; Liposomal Streptomycin; SRY; 47814-83-5    
Trade NameAgri-mycin-17; Plantomycin; Agrept; Rimosidin; AS-50    
CompanyMerck & Co    
IndicationBacterial infectionsApproved    [1]
Structure

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Therapeutic ClassAnti-Bacterial Agents    
CAS NumberCAS 57-92-1
FormularC21H39N7O12    
PubChem Compound IDCID 5999.    
PubChem Substance IDSID 148847.    
ChEBI17076;    
SuperDrug ATC IDA07AA04;    
SuperDrug CAS ID000057921;    
Target30S ribosomal subunitBinder[2][3]
Ref 1Emerging drugs for chemotherapy-induced mucositis. Expert Opin Emerg Drugs. 2008 Sep;13(3):511-22. To Reference
Ref 2Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics. Nature. 2000 Sep 21;407(6802):340-8. To Reference
Ref 3The interaction between streptomycin and ribosomal RNA. Biochimie. 1991 Dec;73(12):1431-8. To Reference



 

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