Therapeutic Targets Database
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TTD Drug ID: DAP000167

Drug Information
NameLamivudine    
SynonymsHSDB 7155; MLS001424097; HHA & Lamivudine; (-)-BCH-189; (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine; STK801940; 3TC & SST; Lamivudine [USAN:BAN:INN]; UNII-2T8Q726O95; Epivir(TM); GR 109714X; Lamivudine (JAN/USP/INN); BCH-790; Zefix; SAM002589994; 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one; LMV; NSC620753; (-)-(2'R,5'S)-1-[2'-Hydroxymethyl-5'-(1,3-oxathiolanyl)]cytosine; 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Galanthus Nivalis Agglutinin (GNA); Lamivir; beta-L-2',3'-Dideoxy-3'-thiacytidine; CHEMBL141; SMR000466319; (-)-BCH 189; GR109714X; (+/-) (Cis)-1-[2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine; 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (+/-) (Cis); 3TC, Zeffix, Heptovir, Epivir, Epivir-HBV, Lamivudine; lamivudine; beta-L-3'-Thia-2',3'-dideoxycytidine; Epivir (TN); Epivir-HBV; DTHC; 2(1H)-Pyrimidinone, 4-amino-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-, (2R-cis)-; C8H11N3O3S; Heptovir; DRG-0126; CHEBI:133986; NCGC00159341-04; D019259; NCGC00159341-03; D00353; Lamivudine [USAN:INN:BAN]; DB00709; 3TC & GNA; 3TC and NV-01; (-)-(2'R,5'S)-1-[2'-Hydroxymethyl-5'-(1,3-oxathiolanyl)]cytosine; 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S); (-)-beta-L-2',3'-Dideoxy-3'-thiacytidine; (-)-SddC; AC1L1TZZ; C07065; (-)-(2'R,5'S)-1-[2'-Hydroxymethyl-5'-(1,3-oxathiolanyl)]cytosine; 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl], (-)(2R,5S) & Hippeastrum hybrid agglutinin( HHA); GR-109714X; BIDD:GT0033; (-)NGPB-21; 3TC; 2',3' Dideoxy 3' thiacytidine; L0217; AC1Q6C34; Bio-0652; S1706_Selleck; SAM001246582; (-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine; MLS000759424; Heptodin; GG-714; Zeffix; Epivir; BCH 189, (-)-; MolPort-002-507-347; LS-2107; CCRIS 9274; 3TC (AIDS INITIATIVE) (AIDS INITIATIVE); 134678-17-4; (-)-2'-Deoxy-3'-thiacytidine; Heptivir; FT-0082667; AC-1416; 4-Amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone; (2R,cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one; 2(1H)-Pyrimidinone, 4-amino-1-((2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-; 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-; BCH189; HMS2051D21; BCH-189; .beta.-L-(-)-2',3'-dideoxy-3'-thiacytidine & Sho-Saiko-To; Lamivudine & GNA; Lamivudine, (2S-cis)-Isomer; 2',3'-Dideoxy-3'-thiacytidine; ZINC00012346; HHA & 3TC; (+/-)-SddC; CID60825; Hepitec; BCH 189; (+/-)-BCH-189; 480434-79-5; 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2(1H)-one; 3'-Thia-2',3'-dideoxycytidine; CPD000466319; (+/-)-3TC    
Trade NameZeffix; Heptovir; Epivir; Epivir-HBV    
CompanyGlaxo Smith Kline Pharmaceuticals    
IndicationHIV infection and chronic hepatitis BApproved    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
   
Therapeutic ClassAnti-HIV Agents    
CAS NumberCAS 134678-17-4
FormularC8H11N3O3S    
PubChem Compound IDCID 60825.    
PubChem Substance IDSID 9277.    
SuperDrug ATC IDJ05AF05;    
SuperDrug CAS ID134678174;    
TargetHBV polymeraseInhibitor[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Nucleos(t)ide analogues for hepatitis B virus: strategies for long-term success. Best Pract Res Clin Gastroenterol. 2008;22(6):1081-92. To Reference



 

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