Therapeutic Targets Database
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TTD Drug ID: DAP000176

Drug Information
NameSibutramine    
SynonymsButramin (TN); Spectrum4_001137; Spectrum_001961; MolPort-002-507-758; HMS2090N17; AKOS004119970; KBio2_005076; TL8000239; 106650-56-0; UNII-WV5EC51866; Sibutraminum [Latin]; Spectrum3_001009; Spectrum2_001686; N-1-(1-(4-chlorophenyl)cyclobutyl)-3-methylbutyl-N,N-dimethylamine HCl; SAM001247105; KBioSS_002516; Sibutraminum; NCGC00092357-02; CPD000238156; KBio2_002508; AC-15773; LS-172014; AC1L1JUC; Meridia; CID5210; I05-0006; Spectrum5_001440; SPBio_001612; CHEMBL1419; DEA No. 1675; 84485-00-7 (hydrochloride); Butramin; SMR000238156; Sibutramine (INN); MLS001401362; Reductil; FT-0082832; HMS2052P05; Sibutramine [INN:BAN]; 1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine; STK802066; D08513; Cyclobutanemethanamine, 1-(4-chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)-; sibutramine; Sibutramina [Spanish]; MLS001066619; Medaria; Sibutramina; STOCK4S-20116; C17H26ClN; KBio2_007644; KBio3_001957; DB01105; C07247; BSPBio_002737; KBioGR_001653; BTS-54524    
Trade NameMeridia; Ectiva; Reductil    
CompanyAbbott Laboratories    
IndicationObesityApproved    [1]
Structure

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Therapeutic ClassAppetite Depressants    
CAS NumberCAS 106650-56-0
FormularC17H26ClN    
PubChem Compound IDCID 5210.    
PubChem Substance IDSID 9456.    
SuperDrug ATC IDA08AA10;    
SuperDrug CAS ID106650560;    
TargetNoradrenergic re-uptakeInhibitor[2][3]
Noradrenergic re-uptakeMultitarget[2][3]
Serotonin re-uptakeInhibitor[2]
Serotonin re-uptakeMultitarget[2]
Ref 1Anti-obesity drugs. Expert Opin Pharmacother. 2008 Jun;9(8):1339-50. To Reference
Ref 2Sibutramine and the management of obesity. Expert Opin Pharmacother. 2004 Mar;5(3):633-42. To Reference
Ref 3Drug treatment of obesity. Baillieres Best Pract Res Clin Endocrinol Metab. 1999 Apr;13(1):131-48. To Reference



 

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