Therapeutic Targets Database
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TTD Drug ID: DAP000256

Drug Information
NameCinacalcet    
SynonymsUNII-UAZ6V7728S; (R)-alpha-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine; N-[(1R)-1-(1-naphthyl)ethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine; AMG073; MolPort-003-845-954; Cinacalcet [INN]; N-[(1R)-1-naphthalen-1-ylethyl]-3-[3-(trifluoromethyl)phenyl]propan-1-amine; N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine; N-((1R)-1-(1-Naphthyl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine; CHEBI:48390; Cinacalcet (USAN); AMG 073; CID156419; HSDB 7318; 364782-34-3 (Hydrochloride); DB01012; Cinacalcet; I14-3270; nchembio.2007.55-comp29; (R)-N-(1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine; TL8001899; 226256-56-0; LS-187374; AC1L4G5X; D03504; NCGC00181002-01    
Trade NameSensipar; Mimpara    
CompanyAmgen    
IndicationCardiovascular disease and kidney diseasePhase III    [1]
HyperparathyroidismApproved    [1]
Structure

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Therapeutic ClassCalcimimetics    
CAS NumberCAS 226256-56-0
FormularC22H22F3N    
PubChem Compound IDCID 156419.    
PubChem Substance IDSID 783756.    
ChEBI48390;    
TargetExtracellular calcium-sensing receptorAgonist[2]
Calcium-sensing receptor Agonist[3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 021688 To Reference
Ref 2Expression and function of the calcium-sensing receptor in juxtaglomerular cells. Hypertension. 2007 Oct;50(4):737-43. Epub 2007 Sep 4. To Reference
Ref 3Amgen. Product Development Pipeline. February 6 2009. To Reference



 

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