Therapeutic Targets Database
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TTD Drug ID: DAP000267

Drug Information
NameMethadone    
SynonymsAmidon; Racemic methadone; CHEMBL651; Heptadone; 3-Hetpanone, 6-(dimethylamino)-4,4-diphenyl-, (R)- (9CI); d-6-(Dimethylamino)-4,4-diphenyl-3-heptanone; Levometadona; Hoechst 10820; LS-74486; 3-HEPTANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, (+-)-; d-Methadone; AC1Q2RLW; (R)-6-(Dimethylamino)-4,4-diphenyl-3-heptanone; Methadone M; 6-Dimethylamino-4,4-diphenyl-3-heptanone; 6-dimethylamino-4,4-di(phenyl)heptan-3-one; Methadon; BRN 3213669; K 174; NINDS_000963; (+-)-Methadone; l-Methadone; Diaminon; Phenadone; Dolophine HCL; 3-Hetpanone, 6-(dimethylamino)-4,4-diphenyl-, (R)-; 6-(dimethylamino)-4,4-diphenylheptan-3-one; BRN 3213667; Dextromethadone; D08195; LS-74487; Dolophin; Heptanon; LS-74485; Methadonum; Heptadone (*Hydrochloride*); (6R)-Methadone; 297-88-1; Ketalgin; Methadone [INN:BAN]; AC1L1HEG; Dolophine (*Hydrochloride*); Adanon; AN 148; HSDB 3119; Tussol; Biscuits; S-(+)-Methadone; L-(+)-Methadone; IDI1_000963; (+/-)-Tussal; Sedo-Rapide; DEA No. 9250; (+/-)-Methadone; DB00333; Levometadona [INN-Spanish]; CHEBI:6807; 6-(Dimethylamino)-4,4-diphenyl-3-heptanone dl-mixture; UNII-UC6VBE7V1Z; Methadone HCL Intensol; KBio1_000963; dl-Methadone; Heptanon (pharmaceutical); Levomethadonum; L-Polamidon; (-)-Methadone; Dollies; l-Polamivet; (R)-6-(Dimethylamino)-4,4-diphenyl-3-hetpanone; MolPort-001-785-650; Polamivet; Metadona [Spanish]; Methadona [Spanish]; A 4624; 3-14-00-00278 (Beilstein Handbook Reference); 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-; Althose; Methaquaione; Hoescht 10820 (*Hydrochloride*); Levothyl; Amidone; Methadonum [INN-Latin]; 1095-90-5 (hydrochloride); Westadone; Levomethadone [INN]; CID4095; Metadona; AC-16055; (-)-(R)-6-(Dimethylamino)-4,4-diphenyl-3-heptanone; 5653-80-5; Algovetin; L000874; DivK1c_000963; AN-148 (*Hydrochloride*); Levomethadonum [INN-Latin]; 76-99-3; 3-HEPTANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, (S)-; Dolly; methadone; EINECS 200-996-9; Phenadone (*Hydrochloride*); Dolophine; (S)-6-(Dimethylamino)-4,4-diphenyl-3-heptanone; Methadonum [Latin]; L-6-(Dimethylamino)-4,4-diphenyl-3-heptanone; Metasedin; Metadone; Polamidone; Metadona [INN-Spanish]; 6S-Methadone; 3-14-00-00279 (Beilstein Handbook Reference); (+)-Methadone; 3-HEPTANONE, 6-(DIMETHYLAMINO)-4,4-DIPHENYL-, L-; C07163; Fenadone (*Hydrochloride*); Methadona; Metadone [DCIT]; BRN 3213668; Methadone (BAN); Heptanon (*Hydrochloride*)    
Trade NameSymoron; Dolophine; Amidone; Methadose; Physeptone; Heptadon    
CompanyEli Lilly and Company    
IndicationCoughApproved    [1]
Structure

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Therapeutic ClassAnalgesics    
CAS NumberCAS 76-99-3
FormularC21H27NO    
PubChem Compound IDCID 4095.    
PubChem Substance IDSID 9372.    
ChEBI6807;    
SuperDrug ATC IDN07BC02;    
SuperDrug CAS ID000076993;    
TargetOpioid receptorAgonist[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 006383 To Reference
Ref 2Methadone treatment and its dangers. Medicina (Kaunas). 2009;45(5):419-25. To Reference
Ref 3mu-Opioid receptor-stimulated synthesis of reactive oxygen species is mediated via phospholipase D2. J Neurochem. 2009 Jun 10. [Epub ahead of print] To Reference



 

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