Therapeutic Targets Database
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TTD Drug ID: DAP000275

Drug Information
NameAlitretinoin    
SynonymsD00094; Ro 1-5488; LGD-1057; Atralin; IDI1_033970; CHEBI:50648; LG-100057; Retisol-A; UPCMLD-DP097; BML2-E05; Alitretinoin; Retinova; Effederm; Spectrum5_001746; NSC122758; STOCK1N-38565; Tretinoina; DB00755; Nexret; 9C-RA; HMS1361K22; 56573-65-0; Tretinoin Zinc Salt; Tretinoine; Tretinoino; R 2625; 9-cis-RA; Avitoin; 187175-63-9; NCGC00161590-06; HMS1361K17; Renova (TN); Atra-IV; Lopac0_001061; AC1L9GWO; IDI1_033965; NCGC00021808-07; NCGC00021808-04; LMPR01090022; Acid, trans-Retinoic; (9cis)-retinoic acid; D02815; b-Retinoic acid; STK801887; AGN-192013; NSC 122758; 9-CIS-RETINOIC ACID; Acid, Vitamin A; MLS002222211; BIDD:PXR0081; CCRIS 7098; DB00982; NCGC00021808-14; A-Acido (Argentina); LGD 1057; BAL-4079; NSC-659772; Spectrum5_001933; AGN 100335; HMS1989K22; LMPR01090019; Tretin M; Solage; I14-2351; Panretin; trans Retinoic Acid; Stieva-A; Retinoic acid; Retacnyl; Aknoten; Alitretinoin [USAN]; HMS2089D20; Acnavit [Denmark]; Panrexin; HMS502N05; Aberela [Norway]; [3H]Retinoic acid; Airol; HSDB 7186; Tri-Luma; Aknefug; BPBio1_000082; CCRIS 3294; Retionic acid; Salt, Tretinoin Zinc; DB00523; LS-1154; .beta.-Retinoic acid; CID449171; Avitoin [Norway]; LGD 100057; NCGC00021808-05; L000833; NCGC00161590-05; MLS000028588; Prestwick_424; NCGC00017280-06; Epi-aberel; SR-01000000239-14; Effederm [France]; alitretinoina; HMS1791K17; Vitinoin; CPD000058245; 9(Z)-Retinoic acid; HMS1791K22; AC1L9MT9; UNII-1UA8E65KDZ; NCGC00017280-17; Aberel; CHEMBL705; Vesanoid (TN); Accutane Roche; EU-0101061; 9-cis Retinoic Acid; HMS1568D16; AC-6824; SAM002264647; Vesnaroid; NCGC00161590-01; 7005-78-9; MolPort-002-507-281; Zinc Salt, Tretinoin; HMS1921D14; A-Vitaminsyre; AC1Q1J2J; UPCMLD-DP097:002; TRETINON; beta-Ra; AKOS000280845; ST057075; R2625_SIGMA; nchembio861-comp8; Acid, Retinoic; C00777; Panretin Gel; ALRT-1057; Tretinoinum; Cordes vas; beta-Retinoic acid; tretinoin liposome; SPECTRUM1502016; 5300-03-8; BAL4079; S1653_Selleck; D014212; nchembio.106-comp3; Retinoate; SR-01000000239; SR-05000013784; ATRA; Dermairol; NCGC00021808-06; alitretinoine; trans-Retinoic acid; NSC 659772; AT-RA; tretinoin; EINECS 206-129-0; Toctino; Retin-A Micro; BSPBio_001495; REA; 1n4h; Spectrum5_001935; 9-cis RA; Stieva-a Forte; 9-CRA; SR-05000013784-1; Prestwick3_000257; Tretinoin (TN); BIDD:GT0483; Panretin (TN); Lsotretinoin; 302-79-4; UNII-5688UTC01R; Retin A (TN); NCGC00161590-04; Avita (TN); Vesanoid; 9 Cis Retinoic Acid; NCGC00161590-03; Atragen; PDT-002-002; I04-0008; MolPort-000-883-857; Acnavit; R0064; Cordes VAS [Germany]; Avita Gel; NCGC00021808-15; BB_NC-1005; BML2-E06; NSC659772; CHEBI:15367; Betarretin; NCGC00161590-07; bmse000562; IDI1_000903; BSPBio_000074; BRN 2057223; AGN 192013; Aberela; 9CRA; 9-cis-Tretinoin; nchembio.154-comp2; all-trans-Tretinoin; BSPBio_001500; LS-1328; Eudyna; HSDB 2169; Prestwick2_000257; Retin-A; Alitretinoin (USAN); CID444795; Vitamin A acid; NCGC00021808-09; CHEMBL38; Ro-04-4079; C15493; NCGC00161590-02; NSC-122758; Panretyn; Renova; HMS1989K17; HMS2092N11; R4643_SIGMA; alitretinoinum; SMR000058245; Retin A; ALRT 1057; MLS001076515; UPCMLD-DP097:001; MLS002207234    
Trade NamePanretin    
CompanyLigand Pharmaceuticals    
IndicationKaposi's sarcomaApproved    [1]
Structure

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Therapeutic ClassAntineoplastic Agents    
CAS NumberCAS 5300-03-8
FormularC20H28O2    
PubChem Compound IDCID 449171.    
PubChem Substance IDSID 509159.    
ChEBI50648;    
SuperDrug ATC IDL01XX22;    
SuperDrug CAS ID005300038;    
TargetRetinoic acid receptor alphaAgonist[2][3][4]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Alitretinoin: a new treatment option for chronic refractory hand eczema. Hautarzt. 2008 Sep;59(9):703-4, 706-9. To Reference
Ref 3Alitretinoin: a comprehensive review. Expert Opin Investig Drugs. 2008 Mar;17(3):437-43. To Reference
Ref 4Oral alitretinoin (9-cis-retinoic acid) therapy for chronic hand dermatitis in patients refractory to standard therapy: results of a randomized, double-blind, placebo-controlled, multicenter trial. Arch Dermatol. 2004 Dec;140(12):1453-9. To Reference



 

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National University of Singapore, Singapore


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