Therapeutic Targets Database
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TTD Drug ID: DAP000329

Drug Information
NameKetotifen    
SynonymsKetotifeno; Ketotiphene; AC1L1GSZ; UNII-X49220T18G; NCGC00015580-09; 116655-74-4; Ketotifene [INN-French]; BRN 3983897; HMS2090F16; BAS 00444483; Prestwick1_000371; STK048448; Ketotifen (INN); NCGC00022572-05; AKOS000541268; Ketotifene; 4-(1-Methyl-piperidin-4-ylidene)-4,9-dihydro-1-thia-benzo[f]azulen-10-one; HC 20-511; BRD-K28936863-051-05-8; Ketotifene fumarate; L000753; Tocris-0784; NCGC00015580-03; Spectrum3_001382; Oprea1_553550; CHEBI:112957; SPBio_001275; BSPBio_002964; 4-(1-Methyl-4-piperidylidene)-9-hydrobenzo[a]thiopheno[3,2-d][7]annulen-10-one; 10H-Benzo[4,5]cyclohepta[1,2-b]thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-, (2E)-2-butenedioate (1:1); KBio2_006042; CAS-34580-14-8; 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-; BSPBio_000521; HSDB 7283; EINECS 252-099-7; BIDD:GT0509; NCGC00022572-04; 4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-benzo(4,5)-cyclohepta(1,2-b)thiophen-10-one; Lopac-K-2628; Ketotiphen; Lopac0_000706; Ketotifenum; NINDS_000111; Spectrum2_001198; STOCK1S-14132; AC-15945; 4,9-Dihydro-4-(1-methyl-4-piperidinylidene)-10H-benzo(4,5)cyclohepta(1,2-b)thiophen-10-one; 10H-Benzo[4,5]cyclohepta[1,2-b]thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-; D08105; KBioSS_000906; C19H19NOS; LS-33820; Prestwick2_000371; ketotifen; Ketotifeno [INN-Spanish]; KBioGR_001289; NCGC00015580-02; IDI1_000111; KBio2_003474; CHEMBL534; Spectrum4_000805; Ketotifenum [INN-Latin]; CID3827; Spectrum_000426; Prestwick3_000371; Alaway (TN); Ketotifin; SPBio_002442; Oprea1_335550; 34580-13-7; KBio3_002184; BPBio1_000575; Prestwick0_000371; 4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one; KBio2_000906; Spectrum5_001395; NCGC00015580-01; AB00053575; DivK1c_000111; KBio1_000111; MolPort-001-933-278; Ketotifen [INN:BAN]; Zaditor; DB00920; NCGC00022572-02    
Trade NameZaditor; Alaway    
CompanyNorvatis Phamaceuticals Corporation    
IndicationAllergic conjunctivitisApproved    [1]
Structure

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Therapeutic ClassAnti-Allergic Agents    
CAS NumberCAS 34580-14-8
FormularC19H19NOS    
PubChem Compound IDCID 3827.    
PubChem Substance IDSID 178305.    
SuperDrug ATC IDR06AX17;    
SuperDrug CAS ID034580137;    
TargetHistamine H1 receptorAntagonist[2][3]
Ref 1Emerging drugs for ocular allergy. Expert Opin Emerg Drugs. 2005 Aug;10(3):505-20. To Reference
Ref 2Intact cell binding for in vitro prediction of sedative and non-sedative histamine H1-receptor antagonists based on receptor internalization. J Pharmacol Sci. 2008 May;107(1):66-79. Epub 2008 Apr 29. To Reference
Ref 3Influence of chronic treatment with H1 receptor antagonists on the anticonvulsant activity of antiepileptic drugs. Pol J Pharmacol. 2001 Jan-Feb;53(1):93-6. To Reference



 

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