Therapeutic Targets Database
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TTD Drug ID: DAP000333

Drug Information
NameDimenhydrinate    
SynonymsNCGC00017026-01; Prestwick_892; 2-(diphenylmethoxy)-N,N-dimethylethanaminium 8-chloro-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurin-7-ide; D00520; CID441281; DB00985; HMS1568F12; CAS-523-87-5; 2-benzhydryloxyethyl(dimethyl)azanium; 8-chloro-1,3-dimethyl-2-oxopurin-6-olate; 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1); Dimenhydrinate (JP15/USP/INN); AC1L9AVV; CHEBI:4604; Dramamine (TN)    
Trade NameDramamine; Gravol; Gravamin; Vertirosan    
CompanyCarter-Horner Corp.    
IndicationNausea and vomitingApproved    [1]
Structure

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Therapeutic ClassAntiemetics    
CAS NumberCAS 523-87-5
FormularC24H28ClN5O3    
PubChem Compound IDCID 441281.    
PubChem Substance IDSID 7847586.    
TargetHistamine H1 receptorAntagonist[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 040519 To Reference
Ref 2Histamine 1 receptor antagonist in symptomatic treatment of renal colic accompanied by nausea: two birds with one stone? Urology. 2009 Jan;73(1):32-6. Epub 2008 Oct 11. To Reference
Ref 3Mechanisms and abuse liability of the anti-histamine dimenhydrinate. Neurosci Biobehav Rev. 2002 Jan;26(1):61-7. To Reference



 

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