Therapeutic Targets Database
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TTD Drug ID: DAP000335

Drug Information
NameLevocabastine    
SynonymsAB00514704; NCGC00179240-01; Livostin; Levocabastina [Spanish]; Livostin (TN); Levocabastinum; Levocabastine [INN:BAN]; Prestwick1_001039; levocabastine; Levocabastina; Levocabastine (INN); BSPBio_001257; Levocabastinum [Latin]; Levocabastin; C26H29FN2O2; SPBio_003108; Prestwick2_001039; Prestwick0_001039; AC1L1GWR; Prestwick3_001039; 79516-68-0; 79547-78-7 (hydrochloride); UNII-H68BP06S81; BRD-K33453211-003-03-2; LS-177481; D08117; CHEMBL560041; DB01106; 1-(4-cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenyl-4-piperidinecarboxylic acid; (3S,4R)-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenylpiperidine-4-carboxylic acid; BPBio1_001382; CID54385; 4-Piperidinecarboxylic acid, 1-(4-cyano-4-(4-fluorophenyl)cyclohexyl)-3-methyl-4-phenyl-, (3S-(1(cis),3alpha,4beta))-    
Trade NameLivostin    
CompanyJanssen Pharmaceutica    
IndicationAllergic conjunctivitisApproved    [1]
Structure

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Therapeutic ClassAnti-Allergic Agents    
CAS NumberCAS 79516-68-0
FormularC26H29FN2O2    
PubChem Compound IDCID 54385.    
PubChem Substance IDSID 667972.    
SuperDrug ATC IDR01AC02;    
SuperDrug CAS ID079516680;    
TargetHistamine H1 receptorAntagonist[2][3]
Ref 1Emerging drugs for ocular allergy. Expert Opin Emerg Drugs. 2005 Aug;10(3):505-20. To Reference
Ref 2Contribution of alpha4beta1 integrin to the antiallergic effect of levocabastine. Biochem Pharmacol. 2008 Sep 15;76(6):751-62. Epub 2008 Jul 15. To Reference
Ref 3Effects of fexofenadine and other antihistamines on components of the allergic response: adhesion molecules. J Allergy Clin Immunol. 2003 Oct;112(4 Suppl):S78-82. To Reference



 

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