Therapeutic Targets Database
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TTD Drug ID: DAP000336

Drug Information
NameChlorpheniramine    
SynonymsClorfeniramina [Italian]; Antagonate; Clorfeniramina; NCGC00162108-01; Chlorphenaminum [INN-Latin]; ISOCLOR; Telachlor; Allergisan; BSPBio_000134; 2-Pyridinepropanamine, .gamma.-(4-chlorophenyl)-N,N-dimethyl-, (S)-; Oprea1_779072; CHEMBL505; 132-22-9; C06905; Prestwick0_000117; Clorfenamina; L000003; KBio1_000596; EINECS 205-054-0; n.-Propanamine, 3-(4-chlorophenyl)-3-(2-pyridyl)-N,N-dimethyl-; 1-(p-Chlorophenyl)-1-(2-pyridyl)-3-dimethylaminopropane; 2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine; Aller-Chlor; Chloroprophenpyridamine; Kloromin; BPBio1_000148; MolPort-002-507-837; Pyridine, 2-(p-chloro-alpha-(2-(dimethylamino)ethyl)benzyl)-; DivK1c_000596; Chlor-Pro; UNII-3U6IO1965U; Prestwick2_000117; NCGC00015227-05; Chloropheniramine; STK736174; 3-(p-Chlorophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine; NINDS_000596; Chlorpheniraminum; Cloropiril; Chlorphenamine [INN]; Chlorphenaminum; 46970-45-0; CHLORPHENIRAMINE (SEE ALSO: CHLORPHENIRAMINE MALEATE (CAS113-92-8)); Chlorphenamine; Prestwick3_000117; Clofeniramina (TN); Chlor-trimeton; Chlo-amine; PiriIton; Piriton; Gen-Allerate; 3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine; 113-92-8; 4-Chloropheniramine; C16H19ClN2; HMS2090M21; CID2725; DB01114; 3-(4-chlorophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine; Novo-Pheniram; Teldrin; HSDB 3032; CHEBI:52010; Haynon; gamma-(4-Chlorophenyl)-gamma-(2-pyridyl)propyldimethylamine; IDI1_000596; Allergican; 2-Pyridinepropanamine, .gamma.-(4-chlorophenyl)-N,N-dimethyl-; Histadur; STOCK5S-99837; Pediacare Allergy Formula; SPBio_002073; LS-754; AC1L1EBQ; Prestwick1_000117; D07398; AKOS001650136; Hayon; Chlorophenylpyridamin; Chlorprophenpyridamine; BRD-A04553218-050-03-0; Chloropiril; Chlorphenamine (INN); Chlor-Trimeton Repetabs; 2-Pyridinepropanamine, gamma-(4-chlorophenyl)-N,N-dimethyl-; Clorfenamina [INN-Spanish]; 1-(p-Chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpropylamine; Lopac0_000261; Polaronil; Phenetron; Clofeniramina; [3H]Chlorpheniramine; gamma-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine; chlorpheniramine; Chlorophenylpyridamine; 42882-96-2    
Trade NameComakin; Chlor-Trimeton; Piriton; Chlor-Tripolon    
CompanySchering-Plough Corporation    
IndicationAllergic rhinitis and uriticariaApproved    [1]
Structure

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Therapeutic ClassAnti-Allergic Agents    
CAS NumberCAS 132-22-9
FormularC16H19ClN2    
PubChem Compound IDCID 2725.    
PubChem Substance IDSID 9122.    
ChEBI52010;    
SuperDrug ATC IDR06AB04;    
SuperDrug CAS ID000132229;    
TargetHistamine H1 receptorAntagonist[2][3][4]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 070797 To Reference
Ref 2Intact cell binding for in vitro prediction of sedative and non-sedative histamine H1-receptor antagonists based on receptor internalization. J Pharmacol Sci. 2008 May;107(1):66-79. Epub 2008 Apr 29. To Reference
Ref 3Combined histamine H1 and H3 receptor blockade produces nasal decongestion in an experimental model of nasal congestion. Am J Rhinol. 1999 Sep-Oct;13(5):391-9. To Reference
Ref 4Inhibition by histamine H1 receptor antagonists of endogenous glibenclamide-sensitive K+ channels in follicle-enclosed Xenopus oocytes. Eur J Pharmacol. 1994 Jan 1;266(1):99-102. To Reference



 

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