Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DAP000337

Drug Information
SynonymsHMS2091I08; NSC 26608; Wellcome preparation 47-83; Spectrum_000854; BRD-K79501723-001-02-0; HSDB 3309; LS-111945; SPECTRUM1500211; NCGC00094634-02; KBio1_001957; KBioSS_001334; Prestwick2_000510; DivK1c_007013; Valoid; Ciclizina; 1-Diphenylmethyl-4-methylpiperazine; 5-23-01-00232 (Beilstein Handbook Reference); Wellcome; Prestwick3_000510; Spectrum3_000368; Compound 47-83; Marezine hydrochloride; C06930; 1-(Diphenylmethyl)-4-methylpiperazine; KBio2_003902; AC1L1N61; 1-Benzhydryl-4-methylpiperazine; WLN: T6N DNTJ AYR&R& D1; N-Methyl-N'-benzhydrylpiperazine; SpecPlus_000917; BRN 0230441; Cyclizinum [INN-Latin]; BW 47-83; AC1Q3ZTI; Reis-fit; EINECS 201-445-5; Spectrum4_000205; Wellcome prepn. 47-83; Nautazine; Emoquil; BSPBio_000439; Ciclizina [INN-Spanish]; N-Methyl-N'-benzyhydrylpiperazine; Spectrum5_001594; CHEMBL648; NSC26608; CYCLIZINE; CHEBI:3994; 82-92-8; NCGC00016421-01; Neo-devomit; CID6726; DB01176; BSPBio_002095; (+-)-1-diphenylmethyl-4-methylpiperazine; BPBio1_000483; UNII-QRW9FCR9P2; KBioGR_000809; SPBio_001187; Prestwick0_000510; KBio3_001315; KBio2_001334; HMS1920A20; Cyclizine hydrochloride; N-Benzhydryl-N'-methylpiperazine; Cyclizinum; Spectrum2_001174; CAS-303-25-3; KBio2_006470; L000701; Oprea1_429421; NCGC00094634-01; SPBio_002360; Cyclizine [INN:BAN:DCF]; Piperazine, 1-(diphenylmethyl)-4-methyl-; Ne-devomit; D03621; (N-Benzhydryl)(N'-methyl)diethylenediamine; 1-Benzhydryl-4-methylpiperazin; Wellcome prepn 47-83; BRD-K79501723-003-03-4; Marezine; Cyclizine chloride; Prestwick1_000510; ( -)-1-Diphenylmethyl-4-methylpiperazine; MolPort-001-798-137; Cyclizine (INN); AB00053084    
Trade NameValoid; Marezine; Marzine; Emoquil    
CompanySeatrace Pharmaceuticals    
IndicationNausea and vomitingApproved    [1]

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
Therapeutic ClassAntiemetics    
CAS NumberCAS 82-92-8
PubChem Compound IDCID 6726.    
PubChem Substance IDSID 9147.    
SuperDrug ATC IDR06AE03;    
SuperDrug CAS ID000082928;    
TargetHistamine H1 receptorAntagonist[2][3][4]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 009495 To Reference
Ref 2Histamine H1-receptor antagonists, promethazine and homochlorcyclizine, increase the steady-state plasma concentrations of haloperidol and reduced haloperidol. Ther Drug Monit. 2003 Apr;25(2):192-6. To Reference
Ref 3Comparison of cyclizine and ondansetron for the prevention of postoperative nausea and vomiting in laparoscopic day-case gynaecological surgery. Anaesthesia. 2002 Jan;57(1):61-5. To Reference
Ref 4Synthesis and combined H1-/H2 antagonist activity of mepyramine, pheniramine and cyclizine derivatives with cyanoguanidine, urea and nitroethenediamine partial structures. Arch Pharm (Weinheim). 1994 Jul;327(7):455-62. To Reference


Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
About BIDD | Databases | Software | Teaching | Research |  Links

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543