Therapeutic Targets Database
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TTD Drug ID: DAP000373

Drug Information
NameProchlorperazine    
SynonymsProchlorpermazine; Prestwick3_000399; P77; Compazine (*Maleate*); 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine; RP 6140; Proclorperazina; Bayer A 173; NCGC00023036-03; Proclorperazina [INN-Spanish]; Spectrum_000840; Prochlorperazinum [INN-Latin]; KBio2_002304; Compro; MolPort-001-611-821; NSC665801; KBio1_000413; Prochlorperazine (JAN/USP/INN); KBio2_006456; 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine; Prochlorperazine maleate; Vertigon; Temetid; BRD-K19352500-332-03-7; 58-38-8; LS-105399; NSC167375; CID4917; Novamin; Probes1_000265; Lopac0_001034; D00493; DivK1c_000413; NCGC00015856-02; 3-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)phenothiazine; Prochloroperazine; Eskatrol; KBioSS_001320; NCI60_022783; KBioGR_002304; N-(gamma-(4'-Methylpiperazinyl-1')propyl)-3-chlorophenothiazine; I06-1771; AC1L1J8I; Compazine; UNII-YHP6YLT61T; Prochlorperazine Edisylate Salt; 3-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)phenothiazine; Prestwick0_000399; Spectrum3_000881; 2-Chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-10H-phenothiazine; Spectrum2_001297; KBioSS_002306; Kronocin; 10H-Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-; CAS-84-02-6; KBio3_002784; Probes2_000307; Emelent; CHEMBL728; L001030; NINDS_000413; Spectrum5_001339; Prochlorperazine mesilate; AB00053532; 84-02-6; 2-Chloro-10-[3-(4-methyl-1-piper- azinyl)propyl]-10H-pheno-thiazine dimaleate; SKF 4657; cMAP_000013; 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine; SMR000058705; SPBio_001333; Chlorperazine; Meterazine; Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine; NCGC00015856-03; Lopac-P-9178; Chlormeprazine; Prochlorpemazine; EINECS 200-379-4; Prochlorperazine dimaleate; Prochlorperazine dihydrobromide; nchembio873-comp71; BRD-K19352500-070-02-5; Chloro-3 (N-methylpiperazinyl-3 propyl)-10 phenothiazine [French]; IDI1_000413; MLS000028600; HSDB 3171; Compro (TN); Phenothiazine, 2-chloro-10-(3-(4-methyl-1-piperazinyl)propyl)-; Prochlorperazin; KBio3_001762; Prochlorperazinum; 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazine; C20H24ClN3S; SPBio_002538; CHLOPERAZINE; DB00433; BSPBio_002394; KBio2_004872; KBio2_001320; prochlorperazine; Prestwick1_000399; KBio2_003888; NSC17478; Prestwick2_000399; BPBio1_000679; 6140 RP; Capazine; CHEBI:8435; Spectrum4_000972; Proclorperazine; Compazine Suppositories; NCGC00015856-01; Prochlorpromazine; KBioGR_001343; Procloperazine; Stemetil; Meterazin; NCGC00015856-07; KBio2_007440; 10H-Phenothiazine, 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-; BSPBio_000617; Prochlorperazine [USAN:INN:BAN:JAN]; Combid; AKOS003600762; Tementil; Nipodal; C07403    
Trade NameCompazine; Stemzine; Buccastem; Stemetil; Phenotil    
CompanyGlaxoSmithKline    
IndicationNausea and vomitingApproved    [1]
Structure

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Therapeutic ClassAntipsychotic Agents    
CAS NumberCAS 58-38-8
FormularC20H24ClN3S    
PubChem Compound IDCID 4917.    
PubChem Substance IDSID 9607.    
ChEBI8435;    
SuperDrug ATC IDN05AB04;    
SuperDrug CAS ID000058388;    
TargetD(2) dopamine receptorAntagonist[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 040058 To Reference
Ref 2In vitro and in vivo characteristics of prochlorperazine oral disintegrating film. Int J Pharm. 2009 Feb 23;368(1-2):98-102. Epub 2008 Oct 15. To Reference
Ref 3Tardive dyskinesia as a result of long-term prochlorperazine use. South Med J. 1996 Oct;89(10):989-91. To Reference



 

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