Therapeutic Targets Database
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TTD Drug ID: DAP000377

Drug Information
NameAtropine    
Synonyms(+/-)-Atropine; b eta-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester; DL-Tropanyl 2-hydroxy-1-phenylpropionate; Atropine Care; Troyl tropate; ST057178; Atropen; CHEBI:15884; Atropen (TN); FT-0082634; Tropic acid, 3-alpha-tropanyl ester; 1alphaH,5alphaH-Tropan-3beta-ol; BRD-A27290375-001-01-8; CID174174; tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate; MEGxp0_001878; [(1S,5R)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl] 3-hydroxy-2-phenyl-propanoate; A0132_SIGMA; HSDB 2199; D00113; ST057655; T0534; dl-Hyoscyamine; MLS000069795; Ocu-Tropine; Atropine Sulfate S.O.P.; Minims; tropan-3alpha-ol; AI3-60219; hyoscyamine; 8-Methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropionate; Atropair; Protamine & Atropine; d1-hyoscyamine; Atropina [Italian]; ATROPINE; C17H23NO3; NCGC00016370-01; atropinium(1+); nchembio.307-comp21; 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol (+-)-tropate (ester) (8CI); 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl tropate; SMR000058248; (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl tropate; SAM002554885; (+-)-hyoscyamine; 51-55-8; [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate; (+/-)-Hyoscyamine; Urised; LS-7203; Bellergal-S; NCGC00142514-01; Atropin; Neo-Diophen; Cytospaz; Isopto Atropine; beta-Phenyl-gamma-oxypropionsaure-tropyl-ester [German]; endo-8-methyl-8-azabicyclo[3.2.1]octan-3-ol; Atropine (USP); NCGC00142514-03; atropinium cation; A2468_SIGMA; (+-)-atropine; CAS-120-29-6; Belladenal; AKOS005137976; tropan-3beta-ol; MolPort-001-742-593; CHEBI:15742; Atropina; AC1L5AX3; beta-Phenyl-gamma-oxypropionsaeure-tropyl-ester [German]; 120-29-6; Atropine [BAN]; Atropt; DB00572; endo-(+/-)-alpha-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester; Tropic acid, ester with tropine; DB04026; Isopto-atropine; bmse000649; Atropinol; HMS2089A16; MLS002695888; 8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate; Benzeneacetic acid, alpha-(hydroxymethyl)-, (3-endo)-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester; 1alphaH,5alphaH-Tropan-3alpha-ol (+-)-tropate (ester); (3-exo)-8-methyl-8-azabicyclo[3.2.1]octan-3-ol; CHEMBL1235490; CHEBI:537621; MolPort-003-986-158; dl-Tropyltropate; NP-010662; Benzeneacetic acid, alpha-(hydroxymethyl)-8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo-(+-)-; 2-Phenylhydracrylic acid 3-alpha-tropanyl ester; Benzeneacetic acid, alpha-(hydroxymethyl)-, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo-(+-)-; Minims Atropine; C01479; Benzeneacetic acid, alpha-(hydroxymethyl)-, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo-(+/-)-; CHEBI:57858; Tropanol; Eyesules; CHEBI:16684; a-Tropine; Hyoscyamine sulfate; (3-endo)-8-methyl-8-azabicyclo[3.2.1]octan-3-ol; Ambap120-29-6; Atropin [German]; 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol (+-)-tropate (ester); OR22908; Tropine (+/-)-tropate; CCRIS 3080; Benzeneacetic acid, alpha-(hydroxymethyl)- 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester endo-(+-)-; Tropine tropate; Benzeneacetic acid, alpha-(hydroxymethyl)-8-methyl-8-azabicyclo(3,2,1)oct-3-yl ester, endo-(+-)-; Benzeneacetic acid, alpha-(hydroxymethyl)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester endo-(+-)-; CPD001906768; (3-endo,8-syn)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-azoniabicyclo[3.2.1]octane; 1alphaH,5alphaH-Tropan-3alpha-ol; (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 3-hydroxy-2-phenylpropanoate; Anaspaz; Atrosulf; Tropine, tropate (ester); AC1Q3XL2; Atropin-flexiolen; DL-Tropyl tropate; I-Tropine; ACon1_000046; EINECS 200-104-8; TL8000018; (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2S)-3-hydroxy-2-phenylpropanoate; (+,-)-Tropyl tropate; MLS001148094    
Trade NameLomotil    
CompanyPfizer Pharmaceuticals    
IndicationOrganophosphate poisoningApproved    [1]
Structure

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Therapeutic ClassAnti-Arrhythmia Agents    
CAS NumberCAS 51-55-8
FormularC17H23NO3    
PubChem Compound IDCID 174174.    
PubChem Substance IDSID 4651.    
ChEBI16684;    
SuperDrug ATC IDA03BA01;    
SuperDrug CAS ID000051558;    
TargetMuscarinic acetylcholine receptor M5Antagonist[2][3][4][5]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 071295 To Reference
Ref 2Additive Protective Effects of Donepezil and Nicotine Against Salsolinol-Induced Cytotoxicity in SH-SY5Y Cells. Neurotox Res. 2009 Mar 20. [Epub ahead of print] To Reference
Ref 3Loss of M2 muscarinic receptor function inhibits development of hypoxic bradycardia and alters cardiac beta-adrenergic sensitivity in larval zebrafish (Danio rerio). Am J Physiol Regul Integr Comp Physiol. 2009 Aug;297(2):R412-20. Epub 2009 Jun 10. To Reference
Ref 4The effects of the antagonists of muscarinic acetylcholine receptor subtypes in rat brain on urinary bladder contraction. Nippon Hinyokika Gakkai Zasshi. 2002 Mar;93(3):427-34. To Reference
Ref 5The muscarinic antagonists aprophen and benactyzine are noncompetitive inhibitors of the nicotinic acetylcholine receptor. Mol Pharmacol. 1987 Nov;32(5):678-85. To Reference



 

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