Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DAP000391

Drug Information
SynonymsTrastuzumab (genetical recombination) (JAN); Herceptin (TN); Trastuzumab; 180288-69-1; Herceptin; D03257; Trastuzumab (INN); Trastuzumab (genetical recombination)    
Trade NameHerceptin    
CompanyRoche & Genentech    
IndicationBreast cancerApproved    [1]
Therapeutic ClassAntineoplastic Agents    
CAS NumberCAS 180288-69-1
PubChem Substance IDSID 17397410.    
SuperDrug ATC IDL01XC03;    
SuperDrug CAS ID180288691;    
TargetReceptor protein-tyrosine kinase erbB-2Antibody[2][3][4]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Her2/neu is not a commonly expressed therapeutic target in melanoma -- a large cohort tissue microarray study. Melanoma Res. 2004 Jun;14(3):207-10. To Reference
Ref 3Nat Rev Drug Discov. 2003 Jan;2(1):38-51.Knockouts model the 100 best-selling drugs--will they model the next 100? To Reference
Ref 4Anti-ErbB-2 monoclonal antibodies and ErbB-2-directed vaccines. Cancer Immunol Immunother. 2002 Jan;50(11):569-87. Epub 2001 Nov 24. To Reference


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