Therapeutic Targets Database
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TTD Drug ID: DAP000404

Drug Information
NameNetilmicin    
SynonymsCID6604416; Netilmicina [INN-Spanish]; AC1L1I7S; O-(2,6-Diamino-2,3,4,6-tetradesoxy-alpha-glycero-4-hexenopyranosyl-(1-4)-O-(3-desoxy-4-C-methyl-3-methylamino-beta-L-arabinopyranosyl-(1-6)-2-desoxy-N1-ethyl-D-streptamin; 1-N-Aethylsisomicin; C21H41N5O7; Prestwick3_001101; D08268; UNII-4O5J85GJJB; C07657; BRN 5316582; NETILMICIN SULFATE; NCGC00016881-01; Netira; NCGC00179265-01; AB00514048; LS-147005; CID4460; Netilyn; D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl-(1-4))-2-deoxy-N1-ethyl-; AR-1G0648; Nettacin; BSPBio_001202; Netilmicine [INN-French]; Netilmicin (INN); CID41859; MolPort-003-849-357; Netilmicinum [INN-Latin]; (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4-amino-3-[[3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-6-(ethylamino)-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol; CAS-56931-57-2; AC1O7GGT; EINECS 260-146-8; SPBio_003081; D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-.beta.-L-arabinopyranosyl-(1->6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-.alpha.-D-glycero-hex-4-enopyranosyl-(1->4)]-2-deoxy-N1-ethyl-; Vectacin; Prestwick2_001101; AC-13442; Sch 20569; 56391-57-2 (sulfate (2:5) salt); (2R,3S,4S,5S)-2-[(1S,2R,3S,4S,6R)-4-amino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-6-(ethylamino)-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol; 2-[4-amino-3-[[3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-6-(ethylamino)-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol; Netilmicine; AC1Q59OC; Netira (TN); Netilmicinum; 56391-56-1; Sch-20569; AC1L9AXV; (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4-amino-3-[[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy]-6-(ethylamino)-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol; Prestwick0_001101; NTL; 4-amino-3-{[3-amino-6-(aminomethyl)-3,4-dihydro-2h-pyran-2-yl]oxy}-6-(ethylamino)-2-hydroxycyclohexyl 3-deoxy-4-c-methyl-3-(methylamino)pentopyranoside; AC1L26N7; CID10480069; CID441306; BPBio1_001324; Prestwick1_001101; CHEMBL1572; HSDB 3584; netilmicin; Netilmicin [INN:BAN]; Netilmicina; D-Streptamine, O-3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl(1-6)-O-(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-glycero-hex-4-enopyranosyl(1-4))-2-deoxy-N(sup 1)-ethyl-; AC1Q57VA; 1-N-Ethylsisomicin    
Trade NameNettacin    
CompanyAbbott Laboratories    
IndicationBacterial infectionsApproved    [1]
Structure

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Therapeutic ClassAntibacterial Agents    
CAS NumberCAS 56391-56-1
FormularC21H41N5O7    
PubChem Compound IDCID 441306.    
PubChem Substance IDSID 9859.    
ChEBI7528;    
SuperDrug ATC IDJ01GB07;    
SuperDrug CAS ID056391561;    
Target30S ribosomal subunitBinder[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Ribosomal resistance in the gentamicin producer organism Micromonospora purpurea. Antimicrob Agents Chemother. 1982 Aug;22(2):231-6. To Reference



 

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