Therapeutic Targets Database
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TTD Drug ID: DAP000407

Drug Information
NameParomomycin    
SynonymsMolPort-002-510-747; Aminosidine, sulfate; 84420-34-8; PAROMOMYCIN I, AMMINOSIDIN, CATENULIN, CRESTOMYCIN, MONOMYCIN A, NEOMYCIN E; Paromomycin sulfate Rx346208; Paromomycin (complex); CHEMBL370143; O-2-Amino-2-deoxy-.alpha.-D-glucopyranosyl-(1->4)-O-[O-2,6-diamino-2,6-dideoxy-.beta.-L-idopyranosyl-(1->3)-.beta.D-ribofuranosyl(1->5)]-2-deoxy-D-streptamine; Human .alpha.-1-antitrypsin & Paromomyin; hATT & Paromomycin; PA1-PA2-PA3-PA4; STOCK1N-08708; 7542-37-2; D07467; AC1L4WW9; catenulin; paromomycin; NSC227228; Hydroxymycin sulfate; DB01421; Paromomycin (INN); CID165580; (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(2R,3S,4R,5S)-5-[(1R,2R,3S,5R,6S)-3,5-diamino-2-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-hydroxycyclohexyl]oxy-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyoxane-3,4-diol; Neomycin E; Humatin; Aminosidin; (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-glucopyranoside; C00832; Paromomycin (TN); Paramomycin Sulfate; Paromomycin I    
Trade NameHumatin    
CompanyKing Pharmaceuticals    
IndicationAcute and chronic intestinal amebiasisApproved    [1]
Structure

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Therapeutic ClassAntibacterial Agents    
CAS NumberCAS 1263-89-4
FormularC23H45N5O14    
PubChem Compound IDCID 165580.    
PubChem Substance IDSID 4090.    
SuperDrug ATC IDA07AA06;    
SuperDrug CAS ID007542372;    
Target30S ribosomal subunitBinder[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 064171 To Reference
Ref 2Aminoglycoside association pathways with the 30S ribosomal subunit. J Phys Chem B. 2009 May 21;113(20):7322-30. To Reference
Ref 330S ribosomal subunit assembly is a target for inhibition by aminoglycosides in Escherichia coli. Antimicrob Agents Chemother. 2002 May;46(5):1546-9. To Reference



 

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