Therapeutic Targets Database
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TTD Drug ID: DAP000414

Drug Information
NameVardenafil    
SynonymsHMS2089K04; 2-[2-ethoxy-5-(4-ethylpiperazin-1-yl)sulfonylphenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4-one; DB00862; Levitra (TN); BRD-K13926615-003-01-7; CID110634; VARDENAFIL, LEVITRA; MolPort-005-975-775; BAY38-9456; STOCK6S-20068; S2515_Selleck; BAY 38-9456; VDN; 2-(2-Ethoxy-5-(4-ethylpiperazin-1-yl-1-sulfonyl)phenyl)-5-methyl-7-propyl-3H-imidazo(5,1-f)(1,2,4)triazin-4-one; LS-111467; UNII-UCE6F4125H; Piperazine, 1-((3-(1,4-dihydro-5-methyl-4-oxo-7-propylimidazo(5,1-f)(1,2,4)triazin-2-yl)-4-ethoxyphenyl)sulfonyl)-4-ethyl-; Vardenafil (INN); HSDB 7304; AC1L3808; CHEMBL1520; 1-((3-(3,4-Dihydro-5-methyl-4-oxo-7-propylimidazo(5,1-f)-as-triazin-2-yl)-4-ethoxyphenyl)sulfonyl)-4-ethylpiperazine; NCGC00167533-01; BSPBio_002392; 2-{2-ethoxy-5-[(4-ethylpiperazin-1-yl)sulfonyl]phenyl}-5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4-ol; STK642629; 2-{2-ETHOXY-5-[(4-ETHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-5-METHYL-7-PROPYLIMIDAZO[5,1-F][1,2,4]TRIAZIN-4(1H)-ONE; 224785-90-4; Vardenafil; D08668; MolPort-002-672-272    
Trade NameLevitra    
CompanyBayer Pharmaceuticals Corporation    
IndicationErectile dysfunctionApproved    [1]
Structure

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Therapeutic ClassAnti-Impotence Agents    
CAS NumberCAS 224785-90-4
FormularC23H32N6O4S    
PubChem Compound IDCID 110634.    
PubChem Substance IDSID 585745.    
SuperDrug ATC IDG04BE09;    
SuperDrug CAS ID224785904;    
TargetCGMP-specific 3',5'-cyclic phosphodiesteraseBinder[2]
Ref 1Designing drugs for the treatment of female sexual dysfunction. Drug Discov Today. 2007 Sep;12(17-18):757-66. Epub 2007 Aug 27. To Reference
Ref 2The effect of vardenafil, a potent and highly selective phosphodiesterase-5 inhibitor for the treatment of erectile dysfunction, on the cardiovascular response to exercise in patients with coronary artery disease. J Am Coll Cardiol. 2002 Dec 4;40(11):2006-12. To Reference



 

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