Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DAP000422

Drug Information
NameParamethasone    
Synonymsparamethasone; Paramethasone [INN:BAN]; Dillar (TN); (6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one; Pregna-1,4-diene-3,20-dione, 6alpha-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-; Parametasone [DCIT]; (6alpha,11beta,16alpha)-6-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; Parametasona; CHEMBL1579; AC1L1LBS; Paramethasonum [INN-Latin]; 6alpha-Fluoro-16alpha-methylprednisolone; Flumethone; LS-175409; D07464; CS 1483; Pregna-1,4-diene-3,20-dione, 6-fluoro-11,17,21-trihydroxy-16-methyl-, (6alpha,11beta,16alpha)-; Parametasona [INN-Spanish]; Cassenne; 53-33-8; C07413; Paramethasone (INN); HSDB 3376; CID5875; Paramethasonum; EINECS 200-169-2; UNII-VFC6ZX3584; Metilar; Paramezone; Cortiden; 16alpha-Methyl-6alpha-fluoroprednisolone; DB01384; Dillar; Parametasone    
IndicationInflammatory diseasesApproved    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
   
Therapeutic ClassAnti-inflammatory Agents    
CAS NumberCAS 53-33-8
FormularC22H29FO5    
PubChem Compound IDCID 5875.    
PubChem Substance IDSID 9617.    
ChEBI7922;    
SuperDrug ATC IDH02AB05;    
SuperDrug CAS ID000053338;    
TargetCorticosteroid-binding globulinBinder[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 012772 To Reference
Ref 2Novel human corticosteroid-binding globulin variant with low cortisol-binding affinity. J Clin Endocrinol Metab. 2000 Jan;85(1):361-7. To Reference
Ref 3A Leu----His substitution at residue 93 in human corticosteroid binding globulin results in reduced affinity for cortisol. J Steroid Biochem Mol Biol. 1992 Aug;42(7):671-6. To Reference



 

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.


Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

 
   
           
 
Computer-aided Drug Design
About BIDD | Databases | Software | Teaching | Research |  Links

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543