Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DAP000422

Drug Information
Synonymsparamethasone; Paramethasone [INN:BAN]; Dillar (TN); (6S,8S,9S,10R,11S,13S,14S,16R,17R)-6-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one; Pregna-1,4-diene-3,20-dione, 6alpha-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-; Parametasone [DCIT]; (6alpha,11beta,16alpha)-6-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; Parametasona; CHEMBL1579; AC1L1LBS; Paramethasonum [INN-Latin]; 6alpha-Fluoro-16alpha-methylprednisolone; Flumethone; LS-175409; D07464; CS 1483; Pregna-1,4-diene-3,20-dione, 6-fluoro-11,17,21-trihydroxy-16-methyl-, (6alpha,11beta,16alpha)-; Parametasona [INN-Spanish]; Cassenne; 53-33-8; C07413; Paramethasone (INN); HSDB 3376; CID5875; Paramethasonum; EINECS 200-169-2; UNII-VFC6ZX3584; Metilar; Paramezone; Cortiden; 16alpha-Methyl-6alpha-fluoroprednisolone; DB01384; Dillar; Parametasone    
IndicationInflammatory diseasesApproved    [1]

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Therapeutic ClassAnti-inflammatory Agents    
CAS NumberCAS 53-33-8
PubChem Compound IDCID 5875.    
PubChem Substance IDSID 9617.    
SuperDrug ATC IDH02AB05;    
SuperDrug CAS ID000053338;    
TargetCorticosteroid-binding globulinBinder[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 012772 To Reference
Ref 2Novel human corticosteroid-binding globulin variant with low cortisol-binding affinity. J Clin Endocrinol Metab. 2000 Jan;85(1):361-7. To Reference
Ref 3A Leu----His substitution at residue 93 in human corticosteroid binding globulin results in reduced affinity for cortisol. J Steroid Biochem Mol Biol. 1992 Aug;42(7):671-6. To Reference


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