Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DAP000494

Drug Information
SynonymsPDSP2_001369; PDSP2_000953; (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine; CHEMBL1175; (S)-Duloxetine; 116539-59-4; (S)-N-Methyl-gamma-(1-naphthalenyloxy)-2-thiophenepropanamine; MLS000758267; (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-amine; LS-172322; SAM001247059; Cymbalta; CHEBI:36795; CPD000449282; (3S)-N-methyl-3-(naphthalen-1-yloxy)-3-(2-thienyl)propan-1-amine; AC-15704; C18H19NOS; PDSP1_001385; Yentreve; NCGC00164559-01; MolPort-003-847-038; AC1L1U0Q; CID60835; HSDB 7368; 2-Thiophenepropanamine, N-methyl-gamma-(1-naphthalenyloxy)-, (S)-; Duloxetine (INN); Yentreve (TN); AC1Q57H7; Duloxetine [INN:BAN]; UNII-O5TNM5N07U; duloxetine; LY 248686; 2-Thiophenepropanamine, N-methyl-gamma-(1-naphthalenyloxy)-, (gammaS)-; D07880; DB00476; PDSP1_000969; HMS2051I05; MLS001423946; SMR000449282; duloxetine, (+)-isomer    
Trade NameCymbalta    
CompanyEli Lilly and Company    
IndicationDepressionApproved    [1]

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
Therapeutic ClassAntidepressive Agents    
CAS NumberCAS 136434-34-9
PubChem Compound IDCID 60835.    
PubChem Substance IDSID 704934.    
TargetNoradrenergic re-uptakeInhibitor[2][3]
Noradrenergic re-uptakeMultitarget[2][3]
Serotonin reuptakeInhibitor[2][3]
Serotonin reuptakeMultitarget[2][3]
Ref 1Emerging treatments for depression. Expert Opin Pharmacother. 2006 Dec;7(17):2323-39. To Reference
Ref 2Multi-target therapeutics: when the whole is greater than the sum of the parts. Drug Discov Today. 2007 Jan;12(1-2):34-42. Epub 2006 Nov 28. To Reference
Ref 3Duloxetine for the treatment of generalized anxiety disorder: a review. Neuropsychiatr Dis Treat. 2009;5:23-31. Epub 2009 Apr 8. To Reference


Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
About BIDD | Databases | Software | Teaching | Research |  Links

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543