Therapeutic Targets Database
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TTD Drug ID: DAP000555

Drug Information
NameRosuvastatin    
SynonymsCHEMBL1496; AKOS000280777; AZD-4522; Rosuvastatin [INN]; 147098-20-2 (Calcium); AC1NR03S; Spectrum5_001695; CID446157; Rosumed; Rosuvast; CID5282455; Creston (TN); (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid; 147098-20-2; HSDB 7317; AKOS005145896; Rosvel; 6-Heptenoic acid, 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-, (3R,5S,6E); TL8006179; AC1L9J7O; Vivacor; Astende; Rosuvas; I06-044; bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino] pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhelpt-6-enoic acid] calcium salt; ZD 4522; Creston; I06-1902; ZD 4522, calcium salt; SPECTRUM1505213; Rosedex; UNII-413KH5ZJ73; AC1O5R1T; ZD-4522; Rosuvastatin calcium; NCGC00178070-01; Pyrimidine Compound, 26; Rovartal; CHEMBL1200361; Rosustatin; S-4522; DB01098; Sinlip; D01915; CID6439133; Crestor; (3R,5S,6E)-7-{4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid; (S-(R*,S*-(E)))-7-(4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid, calcium salt (2:1); CHEBI:38545; Razel; Rosuvastatin hemicalcium; Rosuvastatin; Rosuvastatin calcium (JAN/USAN); Rosuvastatin calcium [USAN]; HMS2093M08; (S-((R*,S*-(E)))- 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl(methylsulfonyl) amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid, calcium salt (2:1); Provisacor; Crestor (TN); 6-Heptenoic acid, 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6E)-; S 4522; LS-181805; HMS1922N09; Simestat; 6-Heptenoic acid, 7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-, calcium salt (2:1), (3R,5S,6E); ZD4522; Rosuvastatin (INN); (E,3R,5R)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoic acid; Bio-0143; (3R,5S,6E)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(ethyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid; calcium (E,3R,5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate; MolPort-000-883-884; Cirantan; (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoic acid; Cresadex; BSPBio_003429; 287714-41-4; Rosimol; LS-187345; D08492; MolPort-003-987-534    
Trade NameCrestor    
CompanyAstraZeneca    
IndicationElevated CRPPhase III    [1]
HypercholesterolemiaApproved    [1]
Structure

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Click to save drug structure in 2D MOL format
   
Therapeutic ClassAnticholesteremic Agents    
CAS NumberCAS 287714-41-4
FormularC22H28FN3O6S    
PubChem Compound IDCID 446157.    
PubChem Substance IDSID 822168.    
ChEBI38545;    
SuperDrug ATC IDC10AA07;    
SuperDrug CAS ID287714414;    
Target3-hydroxy-3-methylglutaryl-coenzyme A reductaseInhibitor[2]
HMG-CoA reductaseInhibitor[3]
Ref 1Emerging drugs for acute and chronic heart failure: current and future developments. Expert Opin Emerg Drugs. 2007 Mar;12(1):75-95. To Reference
Ref 2New dimension of statin action on ApoB atherogenicity. Clin Cardiol. 2003 Jan;26(1 Suppl 1):I7-10. To Reference
Ref 3AstraZeneca. Product Development Pipeline. January 29 2009. To Reference



 

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