Therapeutic Targets Database
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TTD Drug ID: DAP000566

Drug Information
NamePentostatin    
Synonyms59979-24-7; PD-ADI; CHEMBL1580; CID439693; BIDD:GT0136; DB00552; CI-825; 2'-DCF; AC1L97UQ; Oncopent; Coforin; Nipent; Imidazo[4,5-d][1,3]diazepin-8-ol, 3-(2-deoxy-.beta.-D-erythro-pentofuranosyl)-3,4,7,8-tetrahydro-, (8R)-; Pentostatin (JAN/USAN/INN); (8R)-3-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-8-ol; CO-Vidarabine; dCF; 2'-Dexoycoformycin; Vira A deaminase inhibitor; Nipent (TN); 53910-25-1; pentostatin; C02267; Covidarabine; Vidarbine; D00155; (8R)-3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol; PD-81565; 2'-Deoxycoformycin; Deoxycoformycin; Co-V; CL-67310465; (R)-3-(2-Deoxy-.beta.-D-erythro-pentofuranosyl)-3,6,7,8-tetrahydroimidazo(4,5-d)(1,3)diazepin-8-ol; CHEBI:41829    
IndicationHairy cell leukemiaApproved    [1]
Structure

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Therapeutic ClassAntineoplastic Agents    
CAS NumberCAS 53910-25-1
FormularC11H16N4O4    
PubChem Compound IDCID 439693.    
PubChem Substance IDSID 5328.    
SuperDrug ATC IDL01XX08;    
SuperDrug CAS ID053910251;    
TargetAdenosine deaminaseInhibitor[2][3]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Purine nucleoside analogs in indolent non-Hodgkin's lymphoma. Oncology (Williston Park). 2000 Jun;14(6 Suppl 2):13-5. To Reference
Ref 3Acquisition of resistance to anticancer agents by overproduction of target enzymes. Nippon Rinsho. 1997 May;55(5):1030-7. To Reference



 

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