Therapeutic Targets Database
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TTD Drug ID: DAP000569

Drug Information
NameSulindac    
SynonymsSpectrum5_001024; cMAP_000021; Chibret; Copals; Z-5-Fluoro-2-methyl-1-[p-(methlsulfinyl)benzylidene]indene-3-acetic acid; cis-5-Fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid; KBio2_004888; STK802068; SPBio_002206; HMS1921C11; (E)-(1)-5-Fluoro-2-methyl-1-((4-(methylsulphinyl)phenyl)methylene)-1H-indene-3-acetic acid; Spectrum3_001365; 1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-; Sulindacum; S2007_Selleck; C20H17FO3S; Gum copal; AC1Q6YHK; (Z)-5-Fluoro-2-methyl-1-[[4-(methyl-sulfinyl)phenyl]methylene]-1H-indene-3-acetic acid; NCGC00025268-01; KST-1B6530; AB00513800; Lopac-S-8139; Klinoril; Tocris-1707; KBioGR_001571; AR-1A9609; Prestwick_456; NCGC00015970-08; EU-0101070; Clinoril (TN); KBioSS_002322; Clinoril; UNII-M5221THD3M; {(1E)-5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl}acetic acid; Novo-Sundac; HMS2092K15; EINECS 253-819-2; KBio2_007456; Sulindac (JAN/USP/INN); Kendrick Brand of Sulindac; Sulindaco [INN-Spanish]; Sulindac [USAN:BAN:INN:JAN]; NCGC00094349-02; Apo Sulin; EINECS 250-893-8; 6301-55-9; Novopharm Brand of Sulindac; Apo-Sulin; Merck Brand of Sulindac; SPECTRUM1500556; NCGC00025268-03; D013467; C01531; Spectrum4_000876; 38194-50-2; CPD000326718; 5-Fluoro-2-methyl-1-((4-(methylsulphinyl)phenyl)methylene)-1H-indene-3-acetic acid; CID5352; IDI1_000601; Sulindaco; CID1548885; Chemia Brand of Sulindac; Sulindal; Prestwick2_000073; MK 231; (Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl)methylene)-1H-indene-3-acetic acid; Aflodac; SPBio_001451; KBioSS_001506; BRN 2951842; Lopac0_001070; {(1Z)-5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1H-inden-3-yl}acetic acid; Aclin; CHEBI:9352; BRD-A03427350-001-01-3; Copal rosin varnish; 9000-14-0; Nu Sulindac; KBio2_001506; Prestwick1_000073; Cahill May Roberts Brand of Sulindac; 32004-68-5; 53933-60-1; MolPort-002-507-760; Novo Sundac; BSPBio_002890; KBio2_006642; HMS501O03; KBio2_002320; Alphapharm Brand of Sulindac; Sulindacum [INN-Latin]; 2-[6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1-yl]acetic acid; AC1LU7GY; Copal resin; DivK1c_000601; DB00605; D00120; CAS-38194-50-2; UNM-0000306136; NCGC00015970-03; MK-231; KBio2_004074; BB_SC-1128; S8139_SIAL; KBioGR_002320; Apotex Brand of Sulindac; SAM002554933; CID1548887; [(1E)-5-fluoro-2-methyl-1-{[4-(methylsulfinyl)phenyl]methylidene}-1H-inden-3-yl]acetic acid; Arthrocine; BPBio1_000315; Copal; EINECS 258-873-0; (Z)-5-Fluoro-2-methyl-1-[p-(methylsulfinyl)benzylidene]indene-3-acetic acid; cis-5-Fluoro-2-methyl-1-((p-methylsulfinyl)benzylidene)indene-3-acetic acid; S8139_SIGMA; NCGC00094349-01; sulindac; Arthrobid; MLS001304027; KBio1_000601; MLS001056554; CHEMBL1376; UNII-184SNS8VUH; AC-4550; Nu Pharm Brand of Sulindac; MK231; NCGC00015970-01; LS-81610; S 8139; KBio3_002800; AC1L1K5T; AKOS004119989; HMS2089J04; SMR000326718; KBio3_002110; Nu-Pharm Brand of Sulindac; 2-[(3E)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1-yl]acetic acid; SMR000043852; Spectrum2_001326; HMS1568O07; Spectrum_001026; Prestwick3_000073; Sulindac sulfoxide; EINECS 232-527-9; I06-0523; NCGC00015970-02; Resin copal; Kenalin; 2-[(3Z)-6-fluoro-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1-yl]acetic acid; S4429_SIAL; CCRIS 3305; {5-fluoro-2-methyl-1-[4-(methylsulfinyl)benzylidene]-1h-inden-3-yl}acetic acid; AC1LU7GU; Nu-Sulindac; MolPort-003-666-287; SBB058181; NCGC00025268-02; Merck Sharp & Dohme Brand of Sulindac; BSPBio_000285; Mobilin; NINDS_000601; MLS002207124; Prestwick0_000073; BRD-A13946108-001-04-9    
Trade NameClinoril    
CompanyMerck & Co    
IndicationRheumatoid arthritisApproved    [1]
Structure

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Therapeutic ClassAnti-Inflammatory Agents    
CAS NumberCAS 38194-50-2
FormularC20H17FO3S    
PubChem Compound IDCID 1548885.    
PubChem Substance IDSID 3206270.    
ChEBI9352;    
SuperDrug ATC IDM01AB02;    
SuperDrug CAS ID038194502;    
TargetAldose reductaseInhibitor[2][3]
Ref 1New drugs in development for the treatment of endometriosis. Expert Opin Investig Drugs. 2008 Aug;17(8):1187-202. To Reference
Ref 2Biochem Pharmacol. 1983 Jul 1;32(13):1995-8.Inhibition of human lens aldose reductase by flavonoids, sulindac and indomethacin. To Reference
Ref 3Diabetic complications in lens and nerve and their prevention by sulindac or sorbinil: two novel aldose reductase inhibitors. Invest Ophthalmol Vis Sci. 1983 Oct;24(10):1426-9. To Reference



 

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