Therapeutic Targets Database
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TTD Drug ID: DAP000615

Drug Information
NameTadalafil    
SynonymsGF-196960; HSDB 7303; SAM001246586; MLS001424132; CHEMBL779; 1xoz; Cialis (TN); Pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione, 6-(1,3- benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-; S1512_Selleck; Cialis, GF 196960, IC 351, ICOS 351, Tadalafil; LS-187770; Lilly brand of tadalafil; MolPort-002-885-864; IC-351; Pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-; Tadalafil; MLS000759426; Tadalafil [USAN]; KS-1117; Tadanafil; (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione; Tadalafil (JAN/USAN/INN); Pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R-trans)-; ADCIRCA; MLS001195644; D02008; Cialis; GF 196960; Acdirca; 171596-29-5; DB00820; AC1L380B; C429886; FT-0080116; LS-186558; IC 351; HMS2051N17; ICOS 351; (6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione; CPD000466321; UNII-742SXX0ICT; SMR000466321; CHEBI:41488; LS-187015; MLS001165782; Ic351; CID110635; (6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-methylenedioxyphenyl)pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione; ZINC03993855    
Trade NameCialis    
CompanyEli Lilly and Company    
IndicationErectile dysfunctionApproved    [1]
Structure

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Therapeutic ClassAnti-Impotence Agents    
CAS NumberCAS 171596-29-5
FormularC22H19N3O4    
PubChem Compound IDCID 110635.    
PubChem Substance IDSID 585746.    
SuperDrug ATC IDG04BE08;    
SuperDrug CAS ID171596295;    
TargetCGMP-specific 3',5'-cyclic phosphodiesteraseInhibitor[2][3][4]
Ref 1Designing drugs for the treatment of female sexual dysfunction. Drug Discov Today. 2007 Sep;12(17-18):757-66. Epub 2007 Aug 27. To Reference
Ref 2Pulmonary arterial hypertension: the most devastating vascular complication of systemic sclerosis. Rheumatology (Oxford). 2009 Jun;48 Suppl 3:iii25-31. To Reference
Ref 3Phosphodiesterase type 5 inhibitors for the treatment of erectile dysfunction in patients with diabetes mellitus. Int J Impot Res. 2002 Dec;14(6):466-71. To Reference
Ref 4Tadalafil (Cialis) for men with erectile dysfunction. Int J Clin Pract. 2002 May;56(4):300-4. To Reference



 

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