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TTD Drug ID: DAP000631

Drug Information
NameItraconazole    
SynonymsS2476_Selleck; Ambap84625-61-6; 2-butan-2-yl-4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one; AKOS000280875; MLS000863291; 2-butan-2-yl-4-[4-[4-[4-[[(2S,4R)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one; FT-0082511; (1)-cis-4-(4-(4-(4-((2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2,4-dihydro-2-sec-butyl-3H-1,2,4-triazol-3-one; CID9961741; Itraconazole & Nyotran; ITZ; SAM001246679; Itrizole; Sporal; 2-(butan-2-yl)-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one; MolPort-000-883-864; CID55283; CID6917738; CID3793; Triasporn; AC1OCEL7; HMS2090M20; 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-; BIDD:GT0796; AC1L1IRU; DB01167; 84604-65-9; Canadiol; 4-(4-{4-[4-({[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methyl}oxy)phenyl]piperazin-1-yl}phenyl)-2-(1-methylpropyl)-2,4-dihydro-3H-1,2,4-triazol-3-one; Sporanos; TL8005525; Prokanazol; Itraconazol [Spanish]; ITCZ; HMS2051K14; Itraconazolum; 3H-1,2,4-Triazol-3-one, 4-(4-(4-(4-((2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-2,4-dihydro-2-(1-methylpropyl)-; Spherazole; AC1L1GQ5; Sporonox; CPD000058959; Itraconazole oral solution; Itraconazolum [Latin]; R-51211; 2-butan-2-yl-4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one; MLS001148245; MLS000028582; (+-)-1-sec-Butyl-4-(p-(4-(p-(((2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl)methoxy)phenyl)-1-piperazinyl)phenyl)-delta(sup 2)-1,2,4-triazolin-5-one; Itraconazol; C35H38Cl2N8O4; CHEBI:6076; R 51211; AC1Q6EZ3; itraconazole; Sporanox; I0732; Oriconazole; Itraconazole (JAN/USAN); Itraconazole & Nyotran(Liposomal Nystatin); LS-1843; MLS000759472; cis-Itraconazole; D00350; Hyphanox; Sempera; CHEMBL882; UNII-304NUG5GF4; 84625-61-6; Itrizole (TN); BRN 6042047; Intraconazole; NCGC00089812-03; MolPort-003-848-295; SMR000058959; CHEMBL22587; AC-542; I01-1043; Itraconazole [USAN:BAN:INN:JAN]; EINECS 283-347-2; Sporanox (TN); Oriconazole, R51211, Sporanox; 3H-1,2,4-Triazol-3-one, 4-[4-[4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-pipera-zinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl); (+/-)-1-[( R *)- sec -butyl]-4-[ p -[4-[ p -[[(2 R *,4 S *)-2-(2,4-dichlorophenyl)-2-(1 H -1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-(DELTA) 2 1,2,4-triazolin-5-one mixture with (+/-)-1-[( R *)- sec -butyl]-4-[ p -[4- [ p -[[(2 S *,4 R *)-2-(2,4-dichlorophenyl)-2-(1 H -1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl] phenyl]-(DELTA) 2 -1,2,4-triazolin-5-one; Itraconazole & Bovine Lactoferrin; Orungal    
Trade NameSporanox    
CompanyJanssen Pharmaceutica    
IndicationFungal infectionsApproved    [1]
Structure

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Therapeutic ClassAntifungal Agents    
CAS NumberCAS 84625-61-6
FormularC35H38Cl2N8O4    
PubChem Compound IDCID 6917738.    
PubChem Substance IDSID 12012955.    
ChEBI6076;    
SuperDrug ATC IDJ02AC02;    
SuperDrug CAS ID084625616;    
TargetCytochrome P450 51Inhibitor[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 076104 To Reference
Ref 2Voriconazole increases while itraconazole decreases plasma meloxicam concentrations. Antimicrob Agents Chemother. 2009 Feb;53(2):587-92. Epub 2008 Nov 17. To Reference
Ref 3Isolation of genes mediating resistance to inhibitors of nucleoside and ergosterol metabolism in Leishmania by overexpression/selection. J Biol Chem. 1999 Dec 31;274(53):37723-30. To Reference



 

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