TTD Drug ID: DAP000663

Drug Information
Name	Sirolimus
Synonyms	CID5924240; Perceiva; heptadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy; 3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone; nchembio883-comp3; SILA 9268A; DivK1c_006936; KBioGR_000410; Rapamycin Immunosuppressant Drug; AY-22989; UNM-0000358684; MLS000028373; (6H,31H)-pentone, 4,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-; Sirolimus [USAN:BAN:INN]; (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-; NCI60_001851; Sirolimus, Rapamune,Rapamycin; CID5497196; CID5374464; DB00877; Bio2_000855; KBio1_001880; nchembio.79-comp1; Bio2_000375; CID6610346; CID9854379; D00753; Rapamune; CID10795871; Bio1_000782; KBio3_000780; Rapamycin (TN); 1pbk; SMR000058564; C07909; (3-(4-hydroxy-3-methoxycyclohexyl)-1-methylethyl)-10,21-dimethoxy-; CID6711160; CID9854380; MolMap_000043; KBio2_002978; Sirolimus (USAN/INN); WY-090217; SpecPlus_000840; CID5358081; CHEMBL413; LS-143290; CCRIS 9024; Rapamune (TN); NSC 226080; CID9962928; DE-109; R0395_SIAL; CHEBI:100923; Sirolimus (RAPAMUNE); 1fkb; Sirolimus; MS-R001; CBiol_002007; CID6610270; nchembio762-comp1; BiomolKI2_000084; KBio2_000410; HSDB 7284; CID5284616; 53123-88-9; AC1L9ZMV; NCIMech_000355; CID9833581; 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-; rapamycin; Bio1_000293; CID11959112; CID5040; KBio2_005546; CID5460439; CID10213190; NCGC00021305-05; 19E,21R*,23R*,26S*,27S*,34aR*))-; 23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29; CID313006; 23,27-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclohentriacontine; FT-0082351; RPM; 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine; RAP; QTL1_000069; Ambotz53123-88-9; Rapamycin C-7, analog 4; (-)-Rapamycin; SIIA 9268A; UNII-W36ZG6FT64; R0395_SIGMA; C51H79NO13; BIDD:PXR0165; S1039_Selleck; nchembio.100-comp4; CID9962926; Bio1_001271; RAPA; KBioSS_000410; nchembio.2007.42-comp2; LMPK06000003; CHEBI:9168; CID6436030; SMP1_000255; Rapamycin from Streptomyces hygroscopicus; AC1L1JH9; AC-722; A422989, NSC226080; AY 22989; HMS2089A21; CID11949238; NSC226080; CID478951; Rapammune; Antibiotic AY 22989; LCP-Siro; MolPort-003-959-433; Wy 090217; AC1L7MJ9; KBio3_000779; CID6713081
Trade Name	Rapamune
Company	Wyeth
Indication	Dutch Elm disease			Phase I/II    [1]
	Organ rejection			Approved    [1]
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
Therapeutic Class	Immunosuppressive Agents
CAS Number	CAS 53123-88-9
Formular	C51H79NO13
PubChem Compound ID	CID 6436030.
PubChem Substance ID	SID 207443.
ChEBI	9168;
SuperDrug ATC ID	L04AA10;
SuperDrug CAS ID	053123889;
Target	Serine/threonine-protein kinase mTOR			Inhibitor	[2]
Ref 1	Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2	Nat Rev Drug Discov. 2003 Jan;2(1):38-51.Knockouts model the 100 best-selling drugs--will they model the next 100? To Reference

Welcome to sign our Guestbook.

If you find any error in data or bug in web service, please kindly report it to Dr. Zhu.

Dr. Chen Yuzong
Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.