Therapeutic Targets Database
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TTD Drug ID: DAP000709

Drug Information
NameEfavirenz    
SynonymsDB00625; 2H-3,1-Benzoxazin-2-one, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)- (9; HSDB 7163; CPD000466351; (S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; MLS001424087; 2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)-; (S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-ben; DB07709; L-743725; D00896; Efavirenz (JAN/INN); CID64139; SBB066062; DMP-266; Met-Stromal Cell-derived Factor-1.beta. (Human) & Efavirenz; Eravirenz; CHEMBL223228; SMR000466351; MolPort-003-983-924; efavirenz; zoxazin-2-one; 2H-3,1-Benzoxazin-2-one, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)-; Stocrin; MLS000759465; L-743,726; L-741211; (-)-Efavirenz; HMS2090N16; L-743726; Sustiva (TN); (4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one; L 743726; Sustiva (TM); DMP 266; 1ikv; (4S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; AC1L20IX; Sustiva; BIDD:GT0383; EFV; efavirenz, (S)-isomer; Strocin (TM); EFZ; 154598-52-4; HMS2051J08; Met-SDF-1.beta. & Efavirenz; UNII-JE6H2O27P8; AC-19049; SAM001246667; LS-173464; NSC742403; 1ikw; CHEBI:119486; ZINC02020233; 6-chloro-4-(2-cyclopropyl-1-ethynyl)-4-trifluoromethyl-(4S)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one; 2H-3,1-Benzoxazin-2-one, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (S)-; C08088; (S)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one; C14H9ClF3NO2; 2H-3,1-Benzoxazin-2-one, 6-chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-, (4S)-; (4S)-6-Chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one; (4S)-6-chloro-4-(cyclopropylethynyl)-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-2-one    
Trade NameSustiva; Stocrin; Atripla    
IndicationHIV infectionApproved    [1]
Structure

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Therapeutic ClassAnti-HIV Agents    
CAS NumberCAS 154598-52-4
FormularC14H9ClF3NO2    
PubChem Compound IDCID 64139.    
PubChem Substance IDSID 10288.    
SuperDrug ATC IDJ05AG03;    
SuperDrug CAS ID154598524;    
TargetHIV-1 reverse transcriptaseInhibitor[2]
Ref 1Approved antiretroviral drugs. 2009 To Reference
Ref 2Characterization of HIV-1 enzyme reverse transcriptase inhibition by the compound 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid through kinetic and in silico studies. Curr HIV Res. 2009 May;7(3):327-35. To Reference



 

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