Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DAP000737

Drug Information
NameCelecoxib    
SynonymsKBioGR_000723; NCGC00091455-01; SMR000550473; Celebrex (TN); CHEMBL118; Onsenal; KBio2_002351; LS-31667; Celecoxib [Old RN]; KBio2_000912; CPD000550473; CHEBI:41423; CID2662; AI-525; MLS001195656; Solexa; C07589; KBio3_003037; benzenesulfonamide, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-; Celebra; SC-58635; YM177; Medicoxib; S1261_Selleck; Celecoxib (SC-58635); HMS502M15; Celecoxi; 184007-95-2; 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1Hpyrazol-1-yl] benzenesulfonamide; SC 58635; SAM002589995; Spectrum5_001324; Celecox; Spectrum_000432; HSDB 7038; Spectrum4_000182; YM 177; KBio3_002830; KBioSS_000912; KBio1_000893; 4-(5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide; FT-0080064; BSPBio_003596; AC1L1E6K; Celecoxib [USAN]; NINDS_000893; Benzenesulfonamide, 4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)-; DB00482; Celocoxib; SPBio_001512; SC58635; KBio2_004919; HMS2089L18; ZINC02570895; Spectrum2_001576; cMAP_000027; BRD-K02637541-001-02-4; KBio2_003480; Xilebao; NCGC00091455-04; AC-4228; CCRIS 8679; UNM-0000305813; Pfizer brand of celecoxib; NCI60_041049; KBio2_006048; D00567; I01-1033; 4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide; NCGC00091455-03; TL8001323; DivK1c_000893; Spectrum3_001996; C17H14F3N3O2S; 4-[5-(4-METHYLPHENYL)-3-(TRIFLUOROMETHYL)-1H-PYRAZOL-1-YL]BENZENESULFONAMIDE; KBioGR_002351; Benzenesulfonamide,4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl); 169590-42-5; Celebrex; YM-177; BIDD:GT0408; NSC719627; CEL; MLS001304708; TPI-336; KBioSS_002354; 1oq5; Celecoxib (JAN/USAN/INN); Celebrex, Celebra, Celecoxib; SC-58553, SC-58635; Eurocox; IDI1_000893; p-(5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl)benzenesulfonamide; HMS2093I07; C105934; SPECTRUM1503678; KBio2_007487; MolPort-002-885-815; MLS001165684; NCGC00091455-02; celecoxib; CEP-33222; HMS1922G14    
Trade NameCelebrex; Celebra    
CompanyPfizer    
IndicationPainPhase III    [1]
Rheumatoid arthritis and osteoarthritisApproved    [1]
Structure

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Therapeutic ClassAnalgesics    
CAS NumberCAS 169590-42-5
FormularC17H14F3N3O2S    
PubChem Compound IDCID 2662.    
PubChem Substance IDSID 9791.    
ChEBI41423;    
SuperDrug ATC IDM01AH01;    
SuperDrug CAS ID169590425;    
TargetCyclooxygenase-2Inhibitor[2][3][4]
Cyclooxygenase-2Inhibitor[5][4][6][7][8][7][9][10]
Ref 1New drugs in development for the treatment of endometriosis. Expert Opin Investig Drugs. 2008 Aug;17(8):1187-202. To Reference
Ref 2Pfizer. Product Development Pipeline. March 31 2009. To Reference
Ref 3Pfizer. News for Pfizer. March 31 2009. To Reference
Ref 4Mini Rev Med Chem. 2007 Nov;7(11):1108-19.Privileged structures: a useful concept for the rational design of new lead drug candidates. To Reference
Ref 5Celecoxib enhanced the sensitivity of cancer cells to anticancer drugs by inhibition of the expression of P-glycoprotein through a COX-2-Independent Manner. J Cell Biochem. 2009 Jun 26. [Epub ahead of print] To Reference
Ref 6A randomized, clinical trial comparing oral celecoxib 200 mg, celecoxib 400 mg, and ibuprofen 600 mg for acute pain. Acad Emerg Med. 2003 Jan;10(1):22-30. To Reference
Ref 7Valdecoxib (Pharmacia). Curr Opin Investig Drugs. 2002 Feb;3(2):240-5. To Reference
Ref 8Clinical experience with cyclooxygenase-2 inhibitors. Rheumatology (Oxford). 2002 Apr;41 Supp 1:16-22; discussion 35-42. To Reference
Ref 9New and future drug therapies for rheumatoid arthritis. Rheumatology (Oxford). 2000 Jun;39 Suppl 1:36-42. To Reference
Ref 10The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis. Cancer Res. 2000 Sep 15;60(18):5040-4. To Reference



 

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