Therapeutic Targets Database
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TTD Drug ID: DAP000752

Drug Information
NameNaftifine    
Synonyms(E)-N-Cinnamyl-N-methyl-1-naphthalinmethylamin; LS-176454; CHEMBL626; DB00735; Naftifinum; UNII-4FB1TON47A; Naftifin; Prestwick3_001063; Naftifine (INN); (2E)-N-methyl-N-(1-naphthylmethyl)-3-phenyl-2-propen-1-amine; Naftifine HCl; MolPort-003-849-301; CHEBI:126722; (E)-N-Cinnamyl-N-methyl-1-naphthalenemethylamine; N-cinnamyl-N-methyl-1-naphthalenemethylamine hydrochloride; AR-1K5852; 1-Naphthalenemethanamine, N-methyl-N-(3-phenyl-2-propenyl)-, (E)-; Naftifinum [INN-Latin]; CID47641; 65472-88-0; NCGC00179332-01; BRD-K74141488-003-03-9; AB00514711; Naftifine [INN:BAN]; D08245; Naftifina; Naftifina [INN-Spanish]; AC1Q28IA; AC1L2IFX; (E)-N-Cinnamyl-N-methyl-1-naphthylmethylamin; N-Methyl-N-(1-naphthyl methyl)-3-phenyl-2-propen-1-amine(E), hydrochloride; SN 105-843; C08071; Prestwick2_001063; (E)-N-methyl-N-(naphthalen-1-ylmethyl)-3-phenylprop-2-en-1-amine; BSPBio_001046; Naftifine; BPBio1_001152    
Trade NameNaftin    
IndicationFungal infectionsApproved    [1]
Structure

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Therapeutic ClassAntifungal Agents    
CAS NumberCAS 65472-88-0
FormularC21H21N    
PubChem Compound IDCID 47641.    
PubChem Substance IDSID 10271.    
SuperDrug ATC IDD01AE22;    
SuperDrug CAS ID065472880;    
TargetSqualene monooxygenaseInhibitor[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 019356 To Reference
Ref 2Characterization of squalene epoxidase activity from the dermatophyte Trichophyton rubrum and its inhibition by terbinafine and other antimycotic agents. Antimicrob Agents Chemother. 1996 Feb;40(2):443-7. To Reference
Ref 3Mode of action of anti-Candida drugs: focus on terconazole and other ergosterol biosynthesis inhibitors. Am J Obstet Gynecol. 1991 Oct;165(4 Pt 2):1193-9. To Reference



 

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