Therapeutic Targets Database
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TTD Drug ID: DAP000772

Drug Information
NameAcenocoumarol    
Synonyms2-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-4h-chromen-4-one; Mini Sintrom; MLS001074461; Acenocoumarol Alliance Brand; Sintrom; Synthrom; ACENOCOUMAROL; EINECS 205-807-3; LS-55093; Prestwick3_000110; Ciba-Geigy Brand of Acenocoumarol; Nitrowarfarin; Ascumar; AC1Q1Z5F; Neositron; Sinthrome; Sinthrom; Prestwick1_000110; CHEMBL397420; BPBio1_000110; Sincoumar; 3-(alpha-Acetonyl-para-nitrobenzyl)-4-hydroxy-coumarin; G-23,350; Acenocoumarolum; Acenocoumarol [INN]; 4-Hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-2H-1-benzopyran-2-one; Minisintrom; AB-014/25000129; CHEMBL145253; 3-(alpha-(p-Nitrophenol)-beta-acetylethyl)-4-hydroxycoumarin; Acenokumarin [Czech]; 70897-81-3; CHEBI:53766; Prestwick0_000110; 3-(alpha-Acetonyl-4-nitrobenzyl)-4-hydroxycoumarin; AC1L1S7P; BRD-A65051990-001-03-8; Acenokumarin; Syntrom; HMS1568E22; 3-(alpha-(4'-Nitrophenyl)-beta-acetylethyl)-4-hydroxycoumarin; Sinkumar; Acenocumarolo; Acenocumarolo [DCIT]; Nitrophenylacetylethyl-4-hydroxycoumarine; Novartis Brand of Acenocoumarol; Nitrovarfarian; Sintroma; Syncumar; Prestwick2_000110; 4-Hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-2H-chromen-2-one; CID9052; SPBio_002039; Acenocoumarolum [INN-Latin]; 2H-1-Benzopyran-2-one, 4-hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-; UNII-I6WP63U32H; D000074; Acenocumarolum; D07064; Mini-sintrom; Alliance Brand of Acenocoumarol; 2-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]chromen-4-one; Acenocoumarol (INN); 152-72-7; Jsp002948; Coumarin, 3-(alpha-acetonyl-p-nitrobenzyl)-4-hydroxy-; NCGC00179658-01; Nicumalon; 3-(alpha-Acetonyl-p-nitrobenzyl)-4-hydroxycoumarin; BSPBio_000100; Zotil; Nicoumalone; 2H-1-Benzopyran-2-one, 4-hydroxy-3-[1-(4-nitrophenyl)-3-oxobutyl]-; Ciba Geigy Brand of Acenocoumarol; SMR000162652; Prestwick_773; Syncoumar; Mini-sintrom (TN); G 23350; Acenocoumarol Ciba-Geigy Brand; AB00513804; Acenocoumarin; C19H15NO6; DB01418; Acenocoumarol Novartis Brand; HSDB 3201; MLS000539171; 3-(alpha-p-Nitrophenyl-beta-acetylethyl)-4-hydroxycoumarin; G23350; 2H-1-Benzopyran-2-one, 4-hydroxy-3-(1-(4-nitrophenyl)-3-oxobutyl)-, (+-)-; MolPort-002-798-798; G-23350; AR-1E2350; Acenocumarol    
Trade NameSintrom; Sinthrome    
IndicationThrombosisApproved    [1]
Structure

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Therapeutic ClassAnticoagulants    
CAS NumberCAS 152-72-7
FormularC19H15NO6    
PubChem Compound IDCID 9052.    
PubChem Substance IDSID 152231.    
SuperDrug ATC IDB01AA07;    
SuperDrug CAS ID000152727;    
TargetVitamin K epoxide reductase complex subunit 1Inhibitor[2][3][4]
Ref 1Drug information of Acenocoumarol, 2008 To Reference
Ref 2Evaluation of a reverse-hybridization StripAssay for the detection of genetic polymorphisms leading to acenocoumarol sensitivity. Mol Biol Rep. 2009 Jun 28. [Epub ahead of print] To Reference
Ref 3Genotypes associated with reduced activity of VKORC1 and CYP2C9 and their modification of acenocoumarol anticoagulation during the initial treatment period. Clin Pharmacol Ther. 2009 Apr;85(4):379-86. Epub 2009 Feb 18. To Reference
Ref 4Oral anticoagulation and pharmacogenetics: importance in the clinical setting. Rev Med Suisse. 2007 Sep 12;3(124):2030, 2033-4, 2036. To Reference



 

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