Therapeutic Targets Database
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TTD Drug ID: DAP000775

Drug Information
NameDorzolamide    
SynonymsAB00514687; BRD-K48617017-003-03-1; dorzolamide; 120279-96-1; (4S,6S)-4-(ethylamino)-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide; SPBio_003116; BIDD:GT0306; (4S-TRANS)-4-(ETHYLAMINO)-5,6-DIHYDRO-6-METHYL-4H-THIENO(2,3-B)THIOPYRAN-2-SULFONAMIDE-7,7-DIOXIDE; Prestwick2_001116; Trusopt (TN); Prestwick3_001116; Trusopt; MolPort-005-941-739; HMS2089O06; 1cil; (4S,6S)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide; C06969; Prestwick1_001116; Dorzolamide (DZA); AC1NR4NP; Prestwick0_001116; DB04507; BPBio1_001377; CID5284549; (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide; BSPBio_001252; STK645522; Dorzolamide (INN); CHEBI:4702; (4S,6S)-4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid amide; CHEMBL218490; D07871    
Trade NameTrusopt    
CompanyMerck & Co    
IndicationOpen-angle glaucomaApproved    [1]
Structure

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Therapeutic ClassAntihypertensive Agents    
CAS NumberCAS 120279-96-1
FormularC10H16N2O4S3    
PubChem Compound IDCID 5284549.    
PubChem Substance IDSID 9183.    
SuperDrug ATC IDS01EC03;    
SuperDrug CAS ID120279961;    
TargetCarbonic anhydrase IIInhibitor[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Bioorg Med Chem. 2009 Jul 15;17(14):5054-8. Epub 2009 May 30.Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides. To Reference



 

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