Therapeutic Targets Database
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TTD Drug ID: DAP000782

Drug Information
NameAzathioprine    
SynonymsSpectrum_000064; Prestwick_41; A 4638; STOCK1S-27186; AI-981/34845012; A2593_SIAL; AB00443544; EU-0100027; BRD-K60324116-001-01-5; azatiopr in; 6-(Methyl-p-nitro-5-imidazolyl)thiopurine; WLN: T56 BM DN FN HNJ IS- ET5N CNJ A1 DNW; 6-(3-Methyl-5-nitro-3H-imidazol-4-ylsulfanyl)-7H-purine; NCGC00090836-06; KBio2_002427; SMR000427366; Imurek; HMS501N08; Ccucol; EINECS 207-175-4; MolPort-003-665-485; IDI1_000586; 6-(1-Methyl-4-nitroimidazol-5-ylthio)purin; SDCCGMLS-0065415.P001; CBDivE_013132; MolPort-000-745-914; KBio2_000464; Azasan; AB00443544-03; NCGC00094593-01; 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purine; 6-(1-Methyl-p-nitro-5-imidazolyl)thiopurine; SPECTRUM1500133; FT-0083532; Azamun [Czech]; NSC 39084; NCGC00090836-03; 6-(1'-Methyl-4'-nitro-5'-imidazolyl)mercaptopurine; 6-({4-nitro-1-methyl-1H-imidazol-5-yl}sulfanyl)-7H-purine; CCRIS 62; NCGC00015060-12; BW 57322; AI3-50290; NINDS_000586; Purine, 6-((1-methyl-4-nitroimidazol-5-yl)thio)-; Spectrum3_000308; DB00993; KBio1_000586; KBio2_004995; Prestwick3_000094; CHEBI:2948; B. W. 57-322; 6-[(1-Methyl-4-nitroimidazol-5-yl)thio]purine; Azatioprina [INN-Spanish]; CHEMBL1542; MLS001049307; NSC-39084; Azamun; 6-(1-Methyl-p-nitro-5-imidazolyl)-thiopurine; DivK1c_000586; BW-57-322; STOCK1S-20293; NSC39084; C06837; Prestwick1_000094; A4638_SIAL; azathioprine; HMS1920E17; LS-123; KBio3_001376; NCGC00090836-05; ZINC04258316; A4638_SIGMA; 6-(1'-Methyl-4'-nitro-5'-imidazolyl)-mercaptopurine; Spectrum2_000068; 6-[(1-Methyl-4-nitroimidazol-5-yl)- thio] purine; HSDB 7084; Spectrum4_000243; ChemDiv1_002659; 6-(Methyl-p-nitro-5-imidazolyl)-thiopurine; Lopac0_000027; Prestwick0_000094; Imuran; Imurel; Muran; NCGC00015060-01; Azathioprinum; Azathioprinum [INN-Latin]; AC1Q3Z1F; [Methyl(nitroimidazolyl)mercaptopurine]; Prestwick2_000094; HMS1568C10; BSPBio_000048; CAS-446-86-6; KBioGR_002427; BRD-K32821942-001-05-6; KBio2_007563; 6-((1-Methyl-4-nitro-1H-imidazol-5-yl)thio)-1H-purine; AC1L1DAL; Immuran; 55774-33-9 (hydrochloride salt); S1721_Selleck; Azothioprine; SPBio_000255; Azathioprine sodium; HMS2091K19; KBioSS_002433; 6-(1-Methyl-4-nitroimidazol-5-ylthio)purin [Czech]; Purine, 6-[(1-methyl-4-nitroimidazol-5-yl)thio]-; 1H-Purine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-; NCGC00094593-03; AC-4230; BPBio1_000054; Azatioprina; 6-1'-Methyl,4'-nitro,5'-imidazolyl mercaptopurine; KBioGR_000646; 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-Purine; Azathioprin; BW 57-322; 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-7H-purine; UNII-MRK240IY2L; 1H-Purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-; Thiopurine 6-(1-methyl-4-nitroimidazol-5-yl); MolPort-000-764-262; 6-(1-Methyl-4-nitroimidazol-5-yl)thiopurine; KBio2_005600; 446-86-6; NCGC00094593-02; NCGC00090836-02; KBio3_002906; NCGC00015060-04; BSPBio_001876; KBioSS_000464; Azasan (TN); CID2265; NCGC00015060-02; STK831906; Azathioprine (JP15/USP/INN); Azathiopurine; C9H7N7O2S; NCGC00090836-04; Oprea1_375441; cMAP_000046; D00238; SPBio_001987; 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purine; Purine, 6-(1-methyl-4-nitro-5-imidazolylthio)-; Lopac-A-4638; Methylnitroimidazolylmercaptopurine; Oprea1_533384; Spectrum5_000848; Azanin; Oprea1_633462; 9H-Purine, 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-; 1H-Purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-; HMS594I19; NCGC00090836-01; Cytostatics; Azasan, Imuran, Azamun, BW-57-322, NSC-39084, Azathioprine; 6-(3-methyl-5-nitroimidazol-4-yl)sulfanyl-7H-purine; 6-((1-Methyl-4-nitroimidazol-5-yl)thio)purine; KBio2_003032; Azathioprine [USAN:INN:BAN:JAN]; SAM002589938; NCI-C03474; CPD000427366; Imuran (TN); Azatioprin    
Trade NameAzasan; Imuran; Azamun; Imurel    
CompanyGlaxoSmithKline    
IndicationOrgan TransplantApproved    [1]
Structure

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Therapeutic ClassImmunosuppressive Agents    
CAS NumberCAS 446-86-6
FormularC9H7N7O2S    
PubChem Compound IDCID 2265.    
PubChem Substance IDSID 9055.    
ChEBI2948;    
SuperDrug ATC IDL04AX01;    
SuperDrug CAS ID000446866;    
TargetInosine-5'-monophosphate dehydrogenase 1Inhibitor[2][3]
Ref 1Emerging drugs for idiopathic thrombocytopenic purpura in adults. Expert Opin Emerg Drugs. 2008 Jun;13(2):237-54. To Reference
Ref 2IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations. Br J Clin Pharmacol. 2008 Jan;65(1):69-77. Epub 2007 Jul 27. To Reference
Ref 3Immunosuppressive drugs and renal transplantation. G Ital Nefrol. 2005 Nov-Dec;22 Suppl 33:S76-9. To Reference



 

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