Therapeutic Targets Database
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TTD Drug ID: DAP000794

Drug Information
NameSulfinpyrazone    
SynonymsKBioSS_001502; IDI1_000090; USAF GE-13; 4-(2-Benzenesulfinylethyl)-1,2-diphenylpyrazolidine-3,5-dione; Sulfinpirazona; HMS2092K11; 1,2-Diphenyl-3,5-dioxo-4-(2'-phenyl-sulfinyl-aethyl)-pyrazolidin; SMR000058991; MolPort-003-666-286; Anturen; EINECS 200-357-4; ()-Sulfinpyrazone; UNII-V6OFU47K3W; Prestwick_455; sulfinpyrazone (SPZ); Nu-Sulfinpyrazone; DivK1c_000090; S9509_FLUKA; AB00052103; 1,2-Diphenyl-4-(2'-phenylsulfinethyl)-3,5-pyrazolidinedione; Anturane; Anturano; G 28,315; G 28315; Spectrum5_000984; NSC75925; KBio1_000090; 1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]pyrazolidine-3,5-dione; DB01138; D013442; Novartis Brand of Sulfinpyrazone; 3,5-Pyrazolidinedione, 1,2-diphenyl-4-(2-(phenylsulfinyl)ethyl)-; Prestwick1_000290; BSPBio_000200; Diphenylpyrazone; 4-(Phenylsulfoxyethyl)-1,2-diphenyl-3,5-pyrazolidinedione; KBio2_006638; Sulfinpirazona [INN-Spanish]; AC-13602; Prestwick0_000290; AC1L1K4Z; BIDD:PXR0096; Sulfoxyphenylpyrazolidin; NCGC00016255-01; CHEMBL832; SBB058184; SPBio_001447; 1,2-Diphenyl-4-(phenylsulfinylethyl)-3,5-pyrazolidinedione; CPD000058991; NCGC00023932-04; Apotex Brand of Sulfinpyrazone; Nu-Pharm Brand of Sulfinpyrazone; BRD-A36217750-001-05-6; CAS-57-96-5; 3,5-Pyrazolidinedione, 1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]-; Spectrum4_000845; SPECTRUM1500554; NCGC00018267-01; HSDB 3396; Sulfinpyrazone (JP15/USP/INN); Novopyrazone; 1,2-Diphenyl-3,5-dioxo-4-(2-phenylsulfinylethyl)pyrazolidine; NINDS_000090; KBio3_001540; Sulfinpyrazon; Apo-Sulfinpyrazone; (+/-)-SULFINPYRAZONE; HMS1921C09; Enturan; Spectrum2_001324; MLS000028565; 4-[2-(benzenesulfinyl)ethyl]-1,2-diphenylpyrazolidine-3,5-dione; 1,2-Diphenyl-4-[2-(phenylsulfinyl)ethyl-3,5-pyrazolidinedione; BPBio1_000220; C23H20N2O3S; Spectrum3_000590; Anturane (TN); Spectrum_001022; Sulfinpyrazone [USAN:INN:JAN]; 1,2-Diphenyl-3,5-dioxo- 4- (2-phenylsulfinylethyl) pyrazolidine; sulfinpyrazone; KBioGR_001449; S9509_SIGMA; KBio2_004070; SPBio_002419; Nu Sulfinpyrazone; Sulfinpyrazine; Prestwick3_000290; BSPBio_002040; 1,2-Diphenyl-3,5-dioxo-4-(2'-phenyl-sulfinyl-aethyl)-pyrazolidin [German]; D00449; 1,2-Diphenyl-4-(2-(phenylsulfinyl)ethyl)-3,5-pyrazolidinedione; Sulfoxyphenylpyrazolidine; Anturidin; BRN 0713597; HMS500E12; CID5342; 57-96-5; Sulfinpyrazonum; MLS001074941; Anturanil; CHEBI:9342; WLN: T5VNNV EHJ BR& CR& E2SO&R; KBio2_001502; Prestwick2_000290; C07317; LS-128688; Enturen; Anturan; NSC 75925; Sulfinpyrazonum [INN-Latin]; Nu Pharm Brand of Sulfinpyrazone; SAM002554932; NCGC00023932-03; HMS1568J22; Sulphinpyrazone; Apo Sulfinpyrazone    
IndicationGoutApproved    [1]
Structure

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Therapeutic ClassUricosuric Agents    
CAS NumberCAS 57-96-5
FormularC23H20N2O3S    
PubChem Compound IDCID 5342.    
PubChem Substance IDSID 9525.    
ChEBI9342;    
SuperDrug ATC IDB01AC12;    
SuperDrug CAS ID000057965;    
TargetMultidrug resistance-associated protein 1Modulator[2][3][4]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 011556 To Reference
Ref 2Species-dependent transport and modulation properties of human and mouse multidrug resistance protein 2 (MRP2/Mrp2, ABCC2/Abcc2). Drug Metab Dispos. 2008 Apr;36(4):631-40. Epub 2008 Jan 7. To Reference
Ref 3Mutation of a single conserved tryptophan in multidrug resistance protein 1 (MRP1/ABCC1) results in loss of drug resistance and selective loss of organic anion transport. J Biol Chem. 2001 May 11;276(19):15616-24. Epub 2001 Feb 21. To Reference
Ref 4Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q. Genomics. 1999 Sep 15;60(3):295-308. To Reference



 

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