TTD Drug ID: DAP000814

Drug Information
Name	Flumethasone Pivalate
Synonyms	MolPort-002-885-878; Locorten (TN); AC1L9FI1; CHEBI:31620; Flumetasone pivalate; 6,9-Difluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl pivalate; 6.Alpha.,9.alpha.-Difluoro-16.alpha.-methylprednisolone 21-pivalate; 6.Alpha.,9-Difluoro-11.beta.,17,21-trihydroxy-16.a; 6alpha,9-difluoro-11beta,17-dihydroxy-16alpha-methyl-3,20-dioxopregna-1,4-dien-21-yl 2,2-dimethylpropanoate; F0891_SIGMA; Locacorten; Lorinden; AC-2070; ZINC03977985; MLS001077304; Flumethasone pivalate (USP); Locorten; KS-1138; SMR000058824; DB00663; MLS000069558; CID443980; D01464; NSC107680; [2-[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate; FLUMETHASONE PIVALATE; Flumetasone pivalate (JAN/BAN); lpha.-methylpregna-1,4-diene-3,20-dione 21-pivalate; Pregna-1,4-diene-3,20-dione, 21-(2,2-dimethyl-1-oxopropoxy)-6,9-difluoro-11, 17-dihydroxy-16-methyl-, (6.alpha.,11.beta.,16.alpha.)-; CHEMBL1200877; 6alpha,9-Difluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-(2,2-dimethylpropionate); 2002-29-1
Indication	Contact dermatitis			Approved    [1]
Structure	Click to save drug structure in 3D MOL format Click to save drug structure in 2D MOL format
Therapeutic Class	Anti-inflammatory Agents
CAS Number	CAS 2002-29-1
Formular	C27H36F2O6
PubChem Compound ID	CID 443980.
PubChem Substance ID	SID 222338.
ChEBI	31620;
Target	Corticosteroid-binding globulin			Binder	[2][3]
Ref 1	Drug information of Flumethasone Pivalate, 2008 To Reference
Ref 2	Novel human corticosteroid-binding globulin variant with low cortisol-binding affinity. J Clin Endocrinol Metab. 2000 Jan;85(1):361-7. To Reference
Ref 3	A Leu----His substitution at residue 93 in human corticosteroid binding globulin results in reduced affinity for cortisol. J Steroid Biochem Mol Biol. 1992 Aug;42(7):671-6. To Reference

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