Therapeutic Targets Database
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TTD Drug ID: DAP000840

Drug Information
NameDromostanolone    
SynonymsUNII-7DR7H00HDT; 2a-methylandrostan-17b-ol-3-one; dromostanolone; Drostanolonum; HSDB 3319; Drostanolo; 58-19-5; Medrotestron; Dihydro-2alpha-methyltestosterone; (2alpha,5alpha,17beta)-17-hydroxy-2-methylandrostan-3-one; 2-alpha-Methyldihydrotestosterone; Testosterone, 4,5.alpha.-dihydro-2.alpha.-methyl-; C14605; 17-beta-Hydroxy-2-alpha-methyl-5-alpha-androstan-3-one; 5alpha-Androstan-3-one, 17beta-hydroxy-2alpha-methyl-; Metholone; Medrosteron; CCRIS 2777; prometholone; CHEMBL1582; Drostanolona; 2.alpha.-Methyldihydrotestosterone; AC1L1LLU; Drostanolonum [INN-Latin]; Methalone; Drostanolone [INN:BAN]; LS-19397; CHEBI:34838; Testosterone, 4,5alpha-dihydro-2alpha-methyl-; Drostanolona [INN-Spanish]; EINECS 200-367-9; Androstan-3-one, 17-hydroxy-2-methyl-, (2alpha,5alpha,17beta)-; 5.alpha.-Androstan-3-one, 17.beta.-hydroxy-2.alpha.-methyl-; 2-alpha-Methyl-17-beta-hydroxy-5-alpha-androstan-3-one; Dihydro-2.alpha.-methyltestosterone; Androstan-3-one, 17-hydroxy-2-methyl-, (2.alpha.,5.alpha.,17.beta.)-; NSC26198; Drostanolone; Drostanolo [DCIT]; drostanolon; Androstan-3-one, 17-hydroxy-2-methyl-, (2alpha,5alpha,17beta)- (9CI); (2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one; AI3-52812; 17 beta-hydroxy-2 alpha-methyl-5 alpha-androstan-3-one; 17beta-Hydroxy-2alpha-methyl-5alpha-androstan-3-one; AC1Q6OL6; Androstan-3-one, 17-hydroxy-2-methyl-, (2-alpha,5-alpha,17-beta)-; SKI 27719; CID6011; Dihydro-2-alpha-methyltestosterone; AR-1D8078; 5-alpha-Androstan-3-one, 17-beta-hydroxy-2-alpha-methyl-; 2alpha-Methyldihydrotestosterone    
Trade NameDrolban    
IndicationFemale androgenresponsive recurrent mammary cancerApproved    [1]
Structure

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Therapeutic ClassAnabolic Agents    
CAS NumberCAS 521-12-0
FormularC23H36O3    
PubChem Compound IDCID 6011.    
PubChem Substance IDSID 87098.    
ChEBI31523;    
TargetAndrogen receptorBinder[2][3]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2Endocrinological and pathological effects of anabolic-androgenic steroid in male rats. Endocr J. 2004 Aug;51(4):425-34. To Reference
Ref 3Effects of 5-fluorouracil and 2 alpha-methyldihydrotestosterone propionate on the growth of human breast carcinoma MCF-7 in vitro. Eur J Cancer Clin Oncol. 1983 Sep;19(9):1231-7. To Reference



 

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