Therapeutic Targets Database
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TTD Drug ID: DAP000859

Drug Information
NameDoxylamine    
SynonymsHSDB 5184; Ethanamine, N,N-dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)-; Doxylaminum [INN-Latin]; KBio3_001158; Doxylaminum; NCGC00089789-04; 469-21-6; Phenyl-2-pyridylmethyl-beta-N,N-dimethylaminoethyl ether; CID3162; D004319; Prestwick1_000027; N,N-dimethyl-2-[(1-phenyl-1-pyridin-2-ylethyl)oxy]ethanamine; Pyridine, 2-(alpha-(2-(dimethylamino)ethoxy)-alpha-methylbenzyl)-; SPBio_000130; DB00366; NINDS_000841; NCGC00089789-05; BSPBio_000093; Dossilamina [DCIT]; NCGC00089789-02; Prestwick3_000027; CHEBI:51380; MolPort-005-935-542; Prestwick2_000027; C17H22N2O; NCI C60684; KBio1_000841; KBioSS_001494; Spectrum5_000949; DivK1c_000841; AC-15949; Pyridine, 2-[.alpha.-[2-(dimethylamino)ethoxy]-.alpha.-methylbenzyl]-; EINECS 207-414-2; Spectrum_001014; BRD-A44008656-036-05-0; STL018676; 2-(alpha-(2-(Dimethylamino)ethoxy)-alpha-methylbenzyl)pyridine; AB00053466; Doxylamine [INN:BAN]; UNII-95QB77JKPL; L001076; BPBio1_000103; KBio2_006630; 2-Dimethylaminoethoxyphenylmethyl-2-picoline; SPBio_002014; KBioGR_001135; AC1L1FB8; IDI1_000841; Doxilminio; 5-21-03-00508 (Beilstein Handbook Reference); Prestwick0_000027; N,N-dimethyl-2-[1-phenyl-1-(pyridin-2-yl)ethoxy]ethanamine; Spectrum2_000115; Doxylamine (INN); Dossilamina; D07878; doxylamine; KBio2_001494; Doxilminio [INN-Spanish]; CHEMBL1004; doxilamina; Ethanamine, N,N-dimethyl-2-[1-phenyl-1-(2-pyridinyl)ethoxy]-; KBio2_004062; N,N-Dimethyl-2-(1-phenyl-1-(2-pyridinyl)ethoxy)ethanamine; Spectrum4_000528; BRN 0230379; N,N-dimethyl-2-(1-phenyl-1-pyridin-2-ylethoxy)ethanamine; BSPBio_001938; NCGC00021147-08; Spectrum3_000409; LS-127; Lopac0_000348    
Trade NameDolased; Syndol; Mersyndol; Somnil; Dozile; Donormyl; Dormidina; Restavit; Unisom-2; Evanorm; Diclectin    
CompanyIon Healthcare    
IndicationAnxiety and morning sicknessApproved    [1]
Structure

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Therapeutic ClassHypnotics and Sedatives    
CAS NumberCAS 469-21-6
FormularC17H22N2O    
PubChem Compound IDCID 3162.    
PubChem Substance IDSID 153331.    
ChEBI51380;    
SuperDrug ATC IDN05CM21;    
SuperDrug CAS ID000469216;    
TargetHistamine H1 receptorAntagonist[2][3]
Ref 1FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 040167 To Reference
Ref 2First-generation H1 antihistamines found in pilot fatalities of civil aviation accidents, 1990-2005. Aviat Space Environ Med. 2007 May;78(5):514-22. To Reference
Ref 3Steady-state brain concentrations of antihistamines in rats: interplay of membrane permeability, P-glycoprotein efflux and plasma protein binding. Pharmacology. 2004 Oct;72(2):92-8. To Reference



 

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