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TTD Drug ID: DAP000864

Drug Information
NameAmitriptyline    
SynonymsOprea1_479304; NCGC00024433-04; PDSP2_001548; 5-(gamma-Dimethylaminopropylidine)-5H-dibenzo(a,d)(1,4)cycloheptadiene; Amitriptylin; Laroxil; 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-ylidene)-N,N-dimethylpropan-1-amine; NCGC00015095-02; CAS-549-18-8; Amitriptyline [INN:BAN]; Sylvemid; BRN 2217885; CID2160; Amitriptylin [German]; Triptilin; L001041; 5-(3-Dimethylaminopropylidene)-5H-dibenzo[a,d]-10,11-dihydrocycloheptene; Flavyl; DB00321; KBio2_002261; LS-60747; NCGC00015095-03; AKOS000512694; Amitriptilina [INN-Spanish]; Lopac0_000112; N 750; Adepress; Amitriprolidine; 5-(gamma-Dimethylaminopropylidene)-5H-dibenzo[a,d]10,11-dihydrocycloheptene; Prestwick1_000074; Amitriptylinum [INN-Latin]; Amitryptyline; Sarotex; AB00514631; BSPBio_000287; PDSP1_001564; STK525215; NINDS_000766; EINECS 200-041-6; KBio2_005560; STOCK1S-56825; KBio3_001336; Laroxyl; Spectrum4_000146; Amitriptylinum; Prestwick2_000074; Lopac-A-8404; 3-(10,11-Dihydro-5H-dibenzo(a,d)cyclohepten-5-yliden)-N,N-dimethylpropylamin; 5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptatriene; Amitriptyline (INN); CHEBI:2666; NCGC00015095-01; BPBio1_000317; Elavil; Lantron; SPBio_002208; D07448; Triptisol; 30227-34-0 (maleate (1:1)); UNII-1806D8D52K; NSC169910; KBioSS_000424; MolPort-001-662-651; 17086-03-2 (pamoate (2:1)); KBioGR_000592; Elanil; Amytriptiline; Damilan; TP0; IDI1_000766; Spectrum_000044; Tryptanol; 5-(gamma-Dimethylaminopropylidene)-5H-dibenzo(a,d)(1,4)cycloheptadiene; Damilen; Laroxyl (TN); Spectrum3_000298; Amitryptiline; 5-(3'-Dimethylaminopropylidene)-dibenzo-[a,d][1,4]-cycloheptadiene; KBio2_002992; 5-(gamma-Dimethylaminopropylidene)-5H-Dibenzo[a,d][1,4]cycloheptadiene; 10,11-dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo[a,d]cycloheptene; KBioSS_002262; KBio1_000766; CHEMBL629; amitriptyline; AC1L1D20; CCRIS 9174; DivK1c_000766; 10,11-Dihydro-5-(gamma-dimethylaminopropylidene)-5H-dibenzo(a,d)cycloheptene; C06824; Amitriptilina; Amytriptylin; BIDD:GT0115; Spectrum5_000806; KBio2_004829; Amitriptilina [Italian]; 50-48-6; Amitril; KBioGR_002261; MK 230; 5-(3-dimethylaminopropylidene)dibenzo[a,d][1,4]-cycloheptadiene; Spectrum2_000101; Seroten; [3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene)-propyl]-dimethyl-amine; Prestwick0_000074; SPBio_000082; BAS 00269727; Triptanol; BSPBio_001836; KBio3_002741; 10,11-Dihydro-N,N-dimethyl-5H-dibenzo(a,d)heptalene-delta(5),gamma-propylamine; 5-(3'-Dimethylaminopropylidene)-dibenzo-(a,d)(1,4)-cycloheptadiene; Redomex; Damitriptyline; KBio2_007397; Adepril; Ro 4-1575; Proheptadiene; KBio2_000424; BRD-K53737926-003-05-4; 5-(gamma-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene; 549-18-8 (hydrochloride); cMAP_000001; 5-(3-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo(a,d)cycloheptene; Prestwick3_000074; NCGC00015095-10    
Trade NameElavil    
IndicationDepression and chronic painApproved    [1]
Structure

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Click to save drug structure in 2D MOL format
   
Therapeutic ClassAnalgesics    
CAS NumberCAS 50-48-6
FormularC20H23N    
PubChem Compound IDCID 2160.    
PubChem Substance IDSID 9042.    
ChEBI2666;    
SuperDrug ATC IDN06AA09;    
SuperDrug CAS ID000050486;    
TargetNorepinephrine reuptakeMultitarget[2][3]
Serotonin reuptakeInhibitor[2][3]
Serotonin reuptakeMultitarget[2][3]
Norepinephrine reuptakeInhibitor[2][3]
Ref 1Emerging treatments for depression. Expert Opin Pharmacother. 2006 Dec;7(17):2323-39. To Reference
Ref 2Treatment of comorbid pain with serotonin norepinephrine reuptake inhibitors. CNS Spectr. 2008 Jul;13(7 Suppl 11):22-6. To Reference
Ref 3A non-selective (amitriptyline), but not a selective (citalopram), serotonin reuptake inhibitor is effective in the prophylactic treatment of chronic tension-type headache. J Neurol Neurosurg Psychiatry. 1996 Sep;61(3):285-90. To Reference



 

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