Therapeutic Targets Database
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TTD Drug ID: DAP000877

Drug Information
NameBifonazole    
SynonymsCanesten Extra Bifonazol; BRN 0618427; Bifonazol; Bioglan brand of bifonazole; EINECS 262-336-6; Spectrum2_000035; bifonazole; KBio3_002922; Moldina; STK618771; SMR000058970; 1-[phenyl-(4-phenylphenyl)methyl]imidazole; HMS2090K13; (+-)-1-(p,alpha-Diphenylbenzyl)imidazole; MLS000759537; Mycospor (TN); 1H-Imidazole, 1-((1,1'-biphenyl)-4-ylphenylmethyl)-, (+-)-; 60628-96-8; TL8003842; Bay-h-4502; Bifonazolum [INN-Latin]; LS-78073; MLS000028576; Trifonazole; Juventus brand of bifonazole; Bifonazol [INN-Spanish]; Inkeysa brand of bifonazole; SPECTRUM1505309; Bifonazolum; MolPort-003-666-632; Amycor; Bay H-4502; CHEBI:116973; Mycospor; BAY H 4502; Bio-0008; HMS1922B18; SAM001246775; Bifokey; MLS001074074; 1H-Imidazole, 1-((1,1'-biphenyl)-4-ylphenylmethyl)-; DB04794; CPD000058970; 1-(p,alpha-Diphenylbenzyl)imidazole; 5-23-04-00292 (Beilstein Handbook Reference); C036596; NCGC00089815-02; Spectrum3_001970; AC1L1DJN; Bifonazole (JP15/USAN/INN); BRD-A94543220-001-02-3; D01775; CHEMBL277535; NCGC00089815-03; HMS2051F04; 1H-Imidazole, 1-([1,1'-biphenyl]-4-ylphenylmethyl)-; Merck Lipha Sante brand of bifonazole; Azolmen; I01-2098; SPBio_000129; Bifon; CID2378; Dermapharm brand of bifonazole; NCGC00089815-04; Bifomyk; 1-((4-Biphenylyl)phenylmethyl)-1H-imidazole; 1-[4,alpha-Diphenylbenzyl]-imidazole; HMS2093B09; Bayer brand of bifonazole; 1-(alpha-(4-Biphenylyl)benzyl)imidazole; BSPBio_003570; Imidazole, 1-(alpha-(4-biphenylyl)benzyl)-; 1-[biphenyl-4-yl(phenyl)methyl]-1H-imidazole; C22H18N2; VU0239694-7; Canesten brand of bifonazole; AC-15414; (+-)1-([1,1'-Biphenyl]-4-ylphenylmethyl)-1H-imidazole; Bifonazole [USAN:BAN:INN:JAN]    
Trade NameCanespor    
CompanyBayer Pharmaceuticals Corporation    
IndicationFungal infectionsApproved    [1]
Structure

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Therapeutic ClassAntifungal Agents    
CAS NumberCAS 60628-96-8
FormularC22H18N2    
PubChem Compound IDCID 2378.    
PubChem Substance IDSID 183797.    
SuperDrug ATC IDD01AC10;    
SuperDrug CAS ID060628968;    
TargetCytochrome P450 51Inhibitor[2][3][4]
Ref 1Drug information of Bifonazole, 2008 To Reference
Ref 2Investigation of the role of cytochrome P450 2B4 active site residues in substrate metabolism based on crystal structures of the ligand-bound enzyme. Arch Biochem Biophys. 2006 Nov 1;455(1):61-7. Epub 2006 Sep 25. To Reference
Ref 3Bifonazole, a biochemist's view. Dermatologica. 1984;169 Suppl 1:3-9. To Reference
Ref 4Bifonazole and clotrimazole. Their mode of action and the possible reason for the fungicidal behaviour of bifonazole. Arzneimittelforschung. 1984;34(2):139-46. To Reference



 

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