Therapeutic Targets Database
BIDD Pharmainformatics Databases
 
   
 

 

TTD Drug ID: DAP000927

Drug Information
NameTrimethoprim    
SynonymsT2286; NCGC00016055-01; NCGC00024707-05; Toprim; Primosept; KSC-4-158; Velaten; Trimethoprim (JAN/USP/INN); AC1Q48DF; Prestwick0_000208; Lagatrim; Trimethoprimum [INN-Latin]; Trimpex 200; Trimethoprim [USAN:BAN:INN:JAN]; Sinotrim; AC1L1KNQ; Trimetoprim [DCIT]; Spectrum4_000372; Zamboprim; Septrin DS; Proloprim; Omstat; Trimethoprim & VRC3375; Exbesul; Trimetoprima; Bactin; NCGC00024707-03; Polytrim; Bacta; Tocris-0650; Conprim; AB00052118; 92131_FLUKA; SPECTRUM1500595; Cotrimel; Septrin Forte; Trimanyl; BB_SC-2116; SPBio_002116; Bencole; Priloprim; KUC103659N; NCGC00016055-02; Methoprim; Trimetoprim; LS-1627; Urobactrim; CID5578; Bacterial [Antibiotic]; SPBio_000874; Bethaprim; Trimpex (TN); Trimexazole; BPBio1_000215; Resprim; UNII-AN164J8Y0X; Trimexol; EU-0101271; nchembio.221-comp23; HMS501N11; Briscotrim; Trimethopriom; Oraprim; Bacdan; Trimeth/Sulfa; Monoprim; Cidal; Colizole; Oprea1_495058; Sulfoxaprim; Trisul; AB1004879; NCGC00024707-07; trimethoprim; Spectrum2_000937; Trimogal; Futin; nchembio.215-comp11; MLS002303068; I06-0086; Spectrum5_001559; EINECS 212-006-2; Instalac; Roubal; NIH 204; Monotrimin; Fortrim; 46984_RIEDEL; Bacterial; KBio2_003215; Streptoplus; Bacidal; DB00440; Trimethoprimum; Alcorim-F; Wellcoprim; NCGC00024707-04; component of Bactrim; KBio1_000589; Trisulcom; Bactramin; CCRIS 2410; Stopan; Pancidim; Septrin S; D00145; C01965; Trimez-IFSA; CHEBI:45924; 46984_FLUKA; nchembio.108-comp1; Sulmeprim; BSPBio_000195; WR 5949; KBio3_001465; Antrimox; Protrin; Esbesul; Ikaprim; Salvatrim; MolPort-001-826-685; UPCMLD-DP132:001; Anitrim; T 7883; BW 56-72; HSDB 6781; MLS001201740; BRD-K07208025-001-06-5; Prestwick2_000208; Abaprim; Primsol; BW 5672; Trimezol; T7883_SIGMA; Triprim; AI3-52594; Colizole DS; CPD0-1581; ZINC06627681; Roubac; SMP2_000262; Uretrim; Setprin; component of Septra; CHEMBL22; BIDD:GT0190; CAS-738-70-5; IDI1_000589; Purbal; TCMDC-125538; BRN 0625127; Biosulten; HMS1921I03; Bacide; Monotrim; Syraprim; Trimopan; Utetrin; Metoprim; 92131_SIGMA; TL8005108; AKOS001650069; HMS2090D14; BSPBio_002245; HMS2092A10; STK177322; Deprim; ARONIS24118; Espectrin; Prestwick_485; Euctrim; Idotrim; Lagatrim Forte; Prestwick3_000208; Lopac-T-7883; Duocide; Sultrex; NCGC00024707-06; NSC 106568; Kombinax; NINDS_000589; Lopac0_001271; NCGC00024707-01; KBioSS_000647; Prestwick1_000208; KBio2_000647; Resprim Forte; Trimethoprime; KBioGR_000863; Sulfamar; Trimono; Trimetoprim [Polish]; NCGC00016055-06; Proloprim (TN); Sulfamethoprim; MLS000079023; TMP/SMX (MIXTURE)); Uro-D S; Spectrum_000167; Bacin; Lastrim; D014295; Bactoprim; SAM002264649; HMS1568J17; CPD000035999; Xeroprim; Chemotrin; Alprim; Spectrum3_000643; Trimethioprim; Trimpex; Sugaprim; AC-13572; Wellcoprin; Smz-Tmp; NCGC00016055-12; Tmp-Ratiopharm; 738-70-5; NSC-106568; DivK1c_000589; SMR000035999; NIH 204 (VAN); UPCMLD-DP132; Fermagex; AZT + TMP/SMX (mixture) combination; Trimetoprima [INN-Spanish]; Trisural; Trimethoprime [INN-French]; Apo-Sulfatrim; Sulthrim; Trimethopim(TMP); Novotrimel; Antrima; WLN: T6N CNJ BZ DZ E1R CO1 DO1 EO1; Co-Trimoxizole; U-Prin; Tiempe; KBio2_005783; BW-56-72; Bacticel; NCGC00024707-08; Sulfamethoxazole & Trimethoprim; NSC106568; Trisulfam    
Trade NameProloprim; Monotrim; Triprim    
CompanyGlaxoSmithKline    
IndicationUrinary tract infectionsApproved    [1]
Structure

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Click to save drug structure in 2D MOL format
   
Therapeutic ClassAntiinfective Agents    
CAS NumberCAS 738-70-5
FormularC14H18N4O3    
PubChem Compound IDCID 5578.    
PubChem Substance IDSID 5066.    
ChEBI45924;    
SuperDrug ATC IDJ01EA01;    
SuperDrug CAS ID000738705;    
TargetBacterial dihydrofolate reductaseInhibitor[2]
Ref 1Has nature already identified all useful antibacterial targets? Curr Opin Microbiol. 2008 Oct;11(5):387-92. Epub 2008 Oct 6. To Reference
Ref 2Inhibitory properties and X-ray crystallographic study of the binding of AR-101, AR-102 and iclaprim in ternary complexes with NADPH and dihydrofolate reductase from Staphylococcus aureus. Acta Crystallogr D Biol Crystallogr. 2009 Aug;65(Pt 8):751-7. Epub 2009 Jul 10. To Reference



 

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