Therapeutic Targets Database
BIDD Pharmainformatics Databases


TTD Drug ID: DAP001094

Drug Information
SynonymsNatalizumab (INN); Natalizumab; Tysabri; D06886; 189261-10-7; Tysabri (TN)    
Trade NameTysabri; Antegren    
IndicationMultiple sclerosisApproved    [1]
Therapeutic ClassImmunomodulatory Agents    
CAS NumberCAS 189261-10-7
PubChem Substance IDSID 49661786.    
TargetIntegrin alpha-4Antibody[2][3]
Ref 1Disease-modifying agents for multiple sclerosis: recent advances and future prospects. Drugs. 2008;68(17):2445-68. doi: 10.2165/0003495-200868170-00004. To Reference
Ref 2Melanoma complicating treatment with Natalizumab (Tysabri) for multiple sclerosis. J Neurol. 2009 Jul 16. [Epub ahead of print] To Reference
Ref 3Effect of plasma exchange in accelerating natalizumab clearance and restoring leukocyte function. Neurology. 2009 Feb 3;72(5):402-9. To Reference


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