Therapeutic Targets Database
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TTD Drug ID: DAP001131

Drug Information
NameDarifenacin    
SynonymsNCGC00168775-01; DB00496; CID444031; STOCK6S-73577; Darifenacin; D03654; CHEBI:391960; MolPort-005-943-011; (S)-1-(2-(2,3-Dihydro-5-benzofuranyl)ethyl)-alpha,alpha-diphenyl-3-pyrrolidineacetamide; 2-[(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide; Emselex; 2-{(3S)-1-[2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl}-2,2-diphenylacetamide; AC1L9FKY; Darifenacin (USAN/INN); LS-187359; CHEMBL1346; AC-302; 133099-04-4    
Trade NameEnablex; Emselex    
CompanyNorvatis Phamaceuticals Corporation    
IndicationUrinary incontinenceApproved    [1]
Structure

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Therapeutic ClassUrinary antispasmodics    
CAS NumberCAS 133099-04-4
FormularC28H30N2O2    
PubChem Compound IDCID 444031.    
PubChem Substance IDSID 7979027.    
TargetMuscarinic acetylcholine receptor M3Antagonist[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2M(1) and M(3) muscarinic receptors are involved in the release of urinary bladder-derived relaxant factor. Pharmacol Res. 2009 May;59(5):300-5. Epub 2009 Feb 5. To Reference



 

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