Therapeutic Targets Database
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TTD Drug ID: DAP001140

Drug Information
NameAlvimopan    
SynonymsGlycine, N-((2S)-2-(((3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl)methyl)-1-oxo-3-phenylpropyl)-; ]-, [3R-[1(S*),3.alpha.,4.alpha.]]-; DB06274; CID5488548; 2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoyl]amino]acetic acid; Glycine, N-[2-[[4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl; Glycine, N-[(2S)-2-[[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl]-1-oxo-3-phenylpropyl]-; trans-3,4-dimethyl-4-(3-hydroxyphenyl) piperidine; CHEMBL270190; Adl 8-2698; LY 246736; LY246736; Alvimopan; AC1NUQN6; 170098-38-1 (dihydrate); UNII-Q153V49P3Z; Alvimopan anhydrous; I06-1921; 156053-89-3    
Trade NameEntereg    
CompanyGSK    
IndicationPainApproved    [1]
Structure

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Therapeutic ClassAnalgesics    
CAS NumberCAS 156053-89-3
FormularC25H32N2O4    
PubChem Compound IDCID 5488548.    
PubChem Substance IDSID 733432.    
TargetMu-type opioid receptorAntagonist[2]
Ref 1Emerging drugs for postoperative ileus. Expert Opin Emerg Drugs. 2007 Nov;12(4):619-26. To Reference
Ref 2Alvimopan for postoperative ileus. Am J Health Syst Pharm. 2009 Jul 15;66(14):1267-77. To Reference



 

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