Therapeutic Targets Database
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TTD Drug ID: DAP001154

Drug Information
NameImipramine    
SynonymsIntalpram; 113-52-0 (mono-hydrochloride); 5-(3-(Dimethylamino)propyl)-10,11-dihydro-5H-dibenz(b,f)azepine; Norchlorimipramine; Oprea1_200908; KBio2_003963; MolPort-001-783-692; NCGC00024253-03; 1-(3-Dimethylaminopropyl)-4,5-dihydro-2,3,6,7-dibenzazepine; 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-; CHEBI:47499; CAS-113-52-0; L000739; UNII-OGG85SX4E4; CHEMBL11; Promiben; Dynaprin; 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-; N-(gamma-Dimethylaminopropyl)iminodibenzyl; Imipramina; Spectrum2_000990; CPD-11438; N-(.gamma.-Dimethylaminopropyl)iminodibenzyl; Imipramin; HSDB 3100; Spectrum4_000016; Tofranil, base; Tofranil (TN); HMS2089G08; Eupramin; Spectrum_000915; NCGC00015563-01; 10,11-Dihydro-5-(3-(dimethylamino)propyl)-5H-dibenz[b,f]azepine; KBio3_001392; Lopac-I-7379; KBio1_000559; DivK1c_000559; DB08002; KBioGR_000391; NCGC00015563-09; SK-Pramine; Melipramine; NCGC00015563-03; CID3696; IDI1_000559; Imidobenzyle; 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine; Irmin; Psychoforin; NCGC00015563-02; Tofranil (free base); Imiprin; 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-; Imipramine (INN); NSC 169866; BSPBio_000283; 5H-Dibenz(b,f)azepine, 10,11-dihydro-5-(3-(dimethylamino)propyl)-; Tofranil; Imipramine [INN:BAN]; BRN 0256892; Berkomine; nchembio747-comp8; Tofranil (hydrochloride); Imipramina [INN-Spanish]; Prestwick2_000072; KBioSS_001395; BIDD:GT0116; Imipraminum [INN-Latin]; Janimine; 5,6-Dihydro-N-[3-(dimethylamino)propyl]-11H-dibenz[b,e]azepine; CCRIS 9173; EINECS 200-042-1; G-22355; 2,2'-(3-Dimethylaminopropylimino)bibenzyl; Nelipramin; C07049; Censtim; KBio2_006531; Imizin; AC1L1GIE; Dpid; Imizinum; Janimine (hydrochloride); D08070; imipramine; KBio2_001395; Imavate; DB00458; NINDS_000559; 5,6-Dihydro-N-(3-(dimethylamino)propyl)-11H-dibenz(b,e)azepine; NCGC00024253-04; Censtin; Imipramina [Italian]; Spectrum5_000864; Prestwick1_000072; Antideprin; 2,2'-(3-Dimethylaminopropylimino)dibenzyl; Norfranil; Lopac0_000702; Impramine; NSC169866; AB00053486; WLN: T C676 BN&T&J B3N1&1; LS-60467; 10,11-Dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine; BRD-K38436528-003-05-5; Prestwick3_000072; 3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine; Iramil; 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenzo(b,f)azepine; Timolet; Dyna-zina; Spectrum3_000466; BSPBio_002172; SPBio_001059; 5H-Dibenz(b,f)azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl- (9CI); Dimipressin; 5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)-10,11-dihydro-; Imipraminum; Tofraniln A; Melipramin; Prazepine; Declomipramine; 50-49-7; 5H-Dibenz(b,f)azepine,5-[3-(dimethylamino)propyl]-10,11-dihydro-mixed with ethyl alcohol; N-(3-Dimethylaminopropyl)-o-iminodibenzyl; InChI=1/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H; BPBio1_000313; Surplix; SPBio_002204; Pramine; Prestwick0_000072    
Trade NameAntideprin; Deprimin; Deprinol; Depsonil; Dynaprin; Eupramin; Imipramil; Irmin; Janimine; Melipramin; Surplix; Tofranil    
IndicationDepressionApproved    [1]
Structure

Click to save drug structure in 3D MOL format

Click to save drug structure in 2D MOL format
   
Therapeutic ClassAntidepressants    
CAS NumberCAS 50-49-7
FormularC19H24N2    
PubChem Compound IDCID 3696.    
PubChem Substance IDSID 9261.    
ChEBI47499;    
SuperDrug ATC IDN06AA02;    
SuperDrug CAS ID000050497;    
TargetNorepinephrine reuptakeInhibitor[2][3]
Ref 1Emerging treatments for depression. Expert Opin Pharmacother. 2006 Dec;7(17):2323-39. To Reference
Ref 2Invivo antioxidant status: a putative target of antidepressant action. Prog Neuropsychopharmacol Biol Psychiatry. 2009 Mar 17;33(2):220-8. Epub 2008 Nov 30. To Reference
Ref 3Pharmacological profile of neuroleptics at human monoamine transporters. Eur J Pharmacol. 1999 Mar 5;368(2-3):277-83. To Reference



 

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