Therapeutic Targets Database
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TTD Drug ID: DAP001216

Drug Information
NameLatanoprost    
SynonymsXalatan; L1167_SIGMA; propan-2-yl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate; Isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate; AR-202; HMS2051H11; isopropyl (5Z,9alpha,11alpha,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinorprost-5-en-1-oate; PhXA41; CHEBI:6384; AC1NSK8Q; CPD000466354; XA-41; latanoprost; MLS000759468; Isopropyl (5Z,9alpha,11alpha,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinor-prost-5-en-1-oate; CID5311221; XA41; Ambap130209-82-4; TL8000716; CHEMBL1051; HMS2089J17; PhXA34 [as 15(R,S)-isomer]; SMR000466354; latanoprost free acid; Nova-21027; Latanoprost (JAN/USAN/INN); propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate; Catioprost; MolPort-003-942-862; Xalatan (TN); 130209-82-4; Jsp001835; S1254_Selleck; SAM001246671; D00356; PHXA-41; ZINC12468792; MLS001424106    
Trade NameXalatan    
CompanyPfizer Pharmaceuticals    
IndicationOpen-angle glaucoma and ocular hypertensionApproved    [1]
Structure

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Therapeutic ClassAntihypertensive Agents    
CAS NumberCAS 130209-82-4
FormularC26H40O5    
PubChem Compound IDCID 5311221.    
PubChem Substance IDSID 7847422.    
ChEBI6384;    
SuperDrug ATC IDS01EX03;    
SuperDrug CAS ID130209824;    
TargetProstaglandin F2-alpha receptorAgonist[2]
Ref 1Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. To Reference
Ref 2PGF(2alpha) FP Receptor Contributes to Brain Damage Following Transient Focal Brain Ischemia. Neurotox Res. 2009 Jan;15(1):62-70. Epub 2009 Feb 11. To Reference



 

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